Merck
CN

701963

Sigma-Aldrich

聚(乙二醇)二丙烯酸酯

average Mn 6,000, contains ≤1500 ppm MEHQ as inhibitor

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别名:
PEG 二丙烯酸酯
CAS号:
MDL编号:
NACRES:
NA.23

形式

solid

质量水平

分子量

average Mn 6,000

包含

≤1500 ppm MEHQ as inhibitor

反应适用性

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

转变温度

Tm 59-63 °C

Ω端

acrylate

α端

acrylate

聚合物结构设计

shape: linear
functionality: homobifunctional

储存温度

−20°C

SMILES字符串

OCCO.OC(=O)C=C

InChI

1S/C8H10O4/c1-3-7(9)11-5-6-12-8(10)4-2/h3-4H,1-2,5-6H2

InChI key

KUDUQBURMYMBIJ-UHFFFAOYSA-N

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一般描述

聚(乙二醇)二丙烯酸酯(PEGDA)是一种长链,亲水的交联单体广泛用于组织工程。

应用

PEGDA 被广泛用作组织工程应用的支架材料,是因为其生物相容性 和固有的抗蛋白质粘附性能。

它还可被用作 合金剂用于制备用于气体分离的聚合物膜。 比如,聚(醚嵌段酰胺)/PEGDA共混物膜可被 用于分离CO2/H2.

它还可被用作前体,制备用于柔性锂离子电池的聚合物电解质膜。添加PEGDA增强了离子传导,热稳定性和PEMs的机械韧性。

特点和优势

  • 高 亲水性
  • 无毒
  • 生物相容
  • 非免疫原性

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Shaun P Garland et al.
Langmuir : the ACS journal of surfaces and colloids, 30(8), 2101-2108 (2014-02-15)
A growing body of literature broadly documents that a wide array of fundamental cell behaviors are modulated by the physical attributes of the cellular microenvironment, yet in vitro assays are typically carried out using tissue culture plastic or glass substrates
Eyal Karzbrun et al.
Nature physics, 14(5), 515-522 (2018-05-16)
Human brain wrinkling has been implicated in neurodevelopmental disorders and yet its origins remain unknown. Polymer gel models suggest that wrinkling emerges spontaneously due to compression forces arising during differential swelling, but these ideas have not been tested in a
Adel Badria et al.
Journal of materials science. Materials in medicine, 29(11), 175-175 (2018-11-11)
Heart valve diseases remain common in industrialized countries. Bioprosthetic heart valves, introduced as free of anticoagulation therapy alternatives to mechanical substitutes. Still they suffer from long term failure due to calcification. Different treatment methods introduced to inhibit calcification, have so
Sandeep Ameta et al.
Nature communications, 12(1), 842-842 (2021-02-10)
Discovering autocatalytic chemistries that can evolve is a major goal in systems chemistry and a critical step towards understanding the origin of life. Autocatalytic networks have been discovered in various chemistries, but we lack a general understanding of how network
Ruohong Shi et al.
Small (Weinheim an der Bergstrasse, Germany), 16(37), e2002946-e2002946 (2020-08-11)
Hydrogels with the ability to change shape in response to biochemical stimuli are important for biosensing, smart medicine, drug delivery, and soft robotics. Here, a family of multicomponent DNA polymerization motor gels with different polymer backbones is created, including acrylamide-co-bis-acrylamide

商品

2D and 3D scaffold patterning techniques can be applied in the presence of cells using poly(ethylene glycol) (PEG)-based hydrogels. These methods can be applied to any optically transparent, photoactive substrate.

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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