Merck
CN

702153

Sigma-Aldrich

羟基磷灰石

nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)

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别名:
Calcium hydroxide phosphate, Calcium hydroxyphosphate, Pentacalcium hydroxide triphosphate
线性分子式:
[Ca5(OH)(PO4)3]x
CAS号:
分子量:
502.31
MDL编号:
PubChem化学物质编号:
NACRES:
NA.23

形式

dispersion
nanoparticles

质量水平

包含

≤0.025 wt. % dispersant (non-metal based)

浓度

10 wt. % in H2O

表面积

14.3 m2/g , typical

粒径

<200 nm (BET)

pH值(酸碱度)

4-6

密度

1.038 g/mL at 25 °C

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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一般描述

羟基磷灰石(HAP)是一种骨传导生物陶瓷材料,它具有独特的性能可以直接与活体组织结合。它可以通过多种技术制备,如溶液-凝胶法、水热法、多重乳化法、仿生沉积法和电沉积法。

应用

羟基磷灰石可被用于:
  • 一种替代骨的植入材料,因为其化学成分与 骨中无机盐成分相似且有骨诱导特性。
  • 基因和药物载体,因为它具有封装能力和 对许多药物、蛋白有亲和力。
  • 对pH响应的微粒乳化剂。

特点和优势

  • 生物相容的
  • 骨传导的
  • 在 胜利条件下稳定
  • 高机械强度高强度

法律信息

Engi-Mat Co.产品。

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Martin P Reichhardt et al.
Life science alliance, 3(4) (2020-02-27)
The scavenger receptor cysteine-rich (SRCR) family of proteins comprises more than 20 membrane-associated and secreted molecules. Characterised by the presence of one or more copies of the ∼110 amino-acid SRCR domain, this class of proteins have widespread functions as antimicrobial
Thomas Lyon et al.
The Journal of bone and joint surgery. American volume, 95(23), 2088-2096 (2013-12-07)
Recombinant human bone morphogenetic protein-2 (rhBMP-2) applied on an absorbable collagen sponge improves open tibial fracture-healing as an adjunct to unreamed intramedullary nail fixation. We evaluated rhBMP-2 and a new, injectable calcium phosphate matrix (CPM) formulation in acute closed tibial
Tie Liu et al.
Bone, 56(1), 110-118 (2013-06-05)
As an alternative to an autologous bone graft, deproteinized bovine bone (DBB) is widely used in the clinical dentistry. Although DBB provides an osteoconductive scaffold, it is not capable of enhancing bone regeneration because it is not osteoinductive. In order
W Zhang et al.
Journal of dental research, 92(12), 1136-1141 (2013-10-08)
Stem cell-based bone tissue engineering has been recognized as a new strategy for maxillary sinus floor elevation. More rapid bone formation may enhance this technique when simultaneous dental implant placement is desired. Adipose tissue-derived stem cells (ADSCs) and bone marrow
Satyavrata Samavedi et al.
Acta biomaterialia, 9(9), 8037-8045 (2013-06-25)
Calcium phosphate ceramics (CPCs) have been widely used as biomaterials for the regeneration of bone tissue because of their ability to induce osteoblastic differentiation in progenitor cells. Despite the progress made towards fabricating CPCs possessing a range of surface features

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