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Merck
CN

705993

3--25-羟基维生素 D3

98% (CP)

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关于此项目

经验公式(希尔记法):
C27H44O2
化学文摘社编号:
分子量:
400.64
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
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产品名称

3--25-羟基维生素 D3, 98% (CP)

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23-,24-,25+,27-/m1/s1

SMILES string

C[C@@]12[C@](CC[C@]2([H])[C@@H](CCCC(C)(O)C)C)([H])/C(CCC1)=C/C=C3C[C@H](O)CCC/3=C

InChI key

JWUBBDSIWDLEOM-UEGFJKGBSA-N

assay

98% (CP)

form

powder

technique(s)

mass spectrometry (MS): suitable

color

white to off-white

mass shift

M+3

storage temp.

−20°C

Quality Level

Application

3-表-25-羟基维生D3又称为3-epi-25(OH)D3。它是维生素D3在肝脏中形成的代谢物。3-epi-25(OH)D3可作为生物标记物测定维生素D的体内状态。还可作为分析标准品,测定人血清中的3-epi-25(OH)D3分子浓度。

Packaging

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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yosef Dror et al.
The Journal of clinical endocrinology and metabolism, 98(5), 2160-2167 (2013-03-28)
Low serum calcidiol has been associated with multiple comorbidities and mortality but no "safe" range has been found for the upper concentration. We aim to establish the upper threshold of serum calcidiol, beyond which there is an increased risk for
3-epi-25 hydroxyvitamin D concentrations are not correlated with age in a cohort of infants and adults
Strathmann FG, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 413(1-2), 203-206 (2012)
Alex Aregbesola et al.
Journal of epidemiology and community health, 67(6), 533-536 (2013-04-19)
Vitamin D has been suggested to have a role in infection defence and on the immune system. We therefore investigated the effect of serum 25-hydroxyvitamin D₃ (25(OH)D₃) on the risk of incident hospitalised pneumonia in an ageing general population in
P V Pradeep et al.
Journal of postgraduate medicine, 59(1), 4-8 (2013-03-26)
No single factor can predict the occurrence of post total thyroidectomy (TT) hypocalcemia. This study was conducted to look at various factors usually implicated in post TT clinically significant hypocalcemia (CSH) and to develop a scoring system using a combination
Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D
Sempos CT, et al.
British Journal of Clinical Pharmacology, 84(10), 2194-2207 (2018)

商品

Using HybridSPE-Phospholipid, Ascentis Express, and Other LC-MS Workflow Components

Novel sample prep technique coupled with the unique selectivity of the Ascentis Express F5 column enables a fast and simplified bioanalytical method for associated vitamin D metabolites.

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