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Merck
CN

710806

Sigma-Aldrich

18-羟基皮质甾酮

97% (CP)

别名:

4-孕烯-11β,18,21-三醇-3,20-二酮

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关于此项目

经验公式(希尔记法):
C21H30O5
CAS Number:
分子量:
362.46
Beilstein:
2631066
EC 号:
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.24
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质量水平

方案

97% (CP)

表单

powder

技术

mass spectrometry (MS): suitable

储存温度

−20°C

SMILES字符串

O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(CO)[C@@]3([H])CC[C@]4([H])C(CO)=O)=C1

InChI

1S/C21H30O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,14-17,19,22-23,25H,2-7,9-11H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1

InChI key

HFSXHZZDNDGLQN-ZVIOFETBSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Peter et al.
The Journal of clinical endocrinology and metabolism, 80(5), 1622-1627 (1995-05-01)
Aldosterone (Aldo), the most potent mineralocorticoid, is synthesized in the adrenal zona glomerulosa, requiring 11 beta-hydroxylation of 11-deoxycorticosterone (DOC) to form corticosterone (B), hydroxylation at position C18 to form 18-hydroxycorticosterone (18-OHB), and finally oxidation at position C18. There is a
C E Gomez-Sanchez et al.
The Journal of clinical endocrinology and metabolism, 67(2), 322-326 (1988-08-01)
The human adrenal gland can metabolize cortisol to yield steroids oxygenated at the 18 position in a series of reactions similar to those by which corticosterone is converted to 18-hydroxycorticosterone and aldosterone and perhaps catalyzed by the same enzyme. These
M K Birmingham et al.
Endocrine research, 24(3-4), 595-599 (1999-01-15)
A simple semantic differential test was administered twice daily and urinary hormones measured as described previously . The subjects included the patient and two controls, one of whom experienced premenstrual physical, but not mental, discomfort. The test scores of the
Colin Patrick Cantwell et al.
Journal of computer assisted tomography, 32(5), 738-744 (2008-10-03)
To compare low-radiation dose non-enhanced fluorine 18 fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET)/computed tomography (CT) (NE-PET/CT), contrast-enhanced fluorine 18 fluorodeoxyglucose PET/CT (CE-PET/CT), and gadolinium-enhanced liver magnetic resonance imaging (MRI) for the detection and characterization of liver lesions in patients
P Vecsei et al.
Clinical chemistry, 28(3), 453-456 (1982-03-01)
For distinguishing primary aldosteronism from essential hypertension, we use simple direct radioimmunoassays for "aldosterone" (aldosterone and other materials that react with the antibody to aldosterone) and "18-hydroxycorticosterone" (similarly) in unprocessed urine. Patients with primary aldosteronism have high values for "aldosterone."

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