710806
18-羟基皮质甾酮
97% (CP)
别名:
4-孕烯-11β,18,21-三醇-3,20-二酮
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关于此项目
经验公式（希尔记法）:
C21H30O5
化学文摘社编号:
分子量:
362.46
Beilstein:
2631066
EC 号:
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.24
质量水平
方案
97% (CP)
表单
powder
技术
mass spectrometry (MS): suitable
储存温度
−20°C
SMILES字符串
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(CO)[C@@]3([H])CC[C@]4([H])C(CO)=O)=C1
InChI
1S/C21H30O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,14-17,19,22-23,25H,2-7,9-11H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1
InChI key
HFSXHZZDNDGLQN-ZVIOFETBSA-N
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
J Palmer et al.
Electrophoresis, 19(16-17), 3045-3051 (1998-12-31)
Separation of endogenous 17- or 18-hydroxylated corticosteroids (of the 21-hydroxylated 4-pregnen series) as charged chelates in capillary electrophoresis with borate as the ligand is demonstrated. Aldosterone, 18-hydroxycorticosterone, 18-hydroxy-11-deoxycorticosterone, cortisone, cortisol, and 11-deoxycortisol are separated and resolved by 400 mM borate
M Honda et al.
Endocrinologia japonica, 29(5), 529-540 (1982-10-01)
In order to systematically analyze the regulation and metabolism of steroid hormones in a case of primary aldosteronism with multiple lesions, including adenoma and nodular hyperplasia of the left adrenal gland, the amounts of 9 steroids (progesterone (P), 11-deoxycorticosterone (DOC)
Richard J Auchus et al.
The Journal of clinical endocrinology and metabolism, 92(7), 2648-2651 (2007-05-03)
In primary aldosteronism, elevated serum 18-hydroxycorticosterone (18OHB) suggests aldosterone-producing adenoma (APA) rather than bilateral, idiopathic hyperaldosteronism (IHA), but little is known about the relative production of 18OHB and aldosterone (A) in APAs compared with IHA. We measured 18OHB, A, and
P Vecsei et al.
Journal of steroid biochemistry, 19(1A), 345-351 (1983-07-01)
The value of the urine tests: free aldosterone, aldosterone-18-glucuronide, tetrahydroaldosterone 18-hydroxycorticosterone and 18-hydroxydeoxycorticosterone in distinguishing primary aldosteronism from essential hypertension was studied in patients with typical and atypical primary aldosteronism and in patients with essential hypertension. The discriminating function of
Paolo Mulatero et al.
The Journal of clinical endocrinology and metabolism, 97(3), 881-889 (2012-01-13)
Diagnosis of primary aldosteronism (PA) is made by screening, confirmation testing, and subtype diagnosis (computed tomography scan and adrenal vein sampling). However, some tests are costly and unavailable in most hospitals. The aim of the study was to evaluate the
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