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Merck
CN

717142

聚乙二醇(PEG)二硫

average Mn 1,000, thiol

别名:

聚乙二醇二硫醇

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关于此项目

线性分子式:
HSCH2CH2(OCH2CH2)nSH
UNSPSC Code:
12162002
NACRES:
NA.23
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产品名称

聚乙二醇(PEG)二硫, average Mn 1,000

form

solid

Quality Level

mol wt

average Mn 1,000

reaction suitability

reagent type: cross-linking reagent
reactivity: thiol reactive

mp

29-33 °C

Ω-end

thiol

α-end

thiol

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

2-8°C

Application

硫醇官能化的纳米颗粒可用于粘膜粘附药物递送,合成二硫醇封端的两亲性二嵌段共聚物,双配位基二硫醇-聚(乙二醇)-聚(d,l-丙交酯)(SH2-PEG-PDLLA)。通过简单的配体交换,金纳米颗粒可以很容易地用PEG二硫醇官能化。

Other Notes

分子量:Mn为900-1,100


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pictograms

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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分析证书(COA)

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商品

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

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Jian Yang et al.
Biomacromolecules, 15(4), 1346-1354 (2014-03-13)
Thiol-modified nanoparticles have potential applications in mucoadhesive drug delivery and have been examined in this regard for topical ocular delivery. In this paper we provide a simple method for the synthesis of a dithiol terminated amphiphilic diblock copolymer. Bidentate dithiol-poly(ethylene
Nadeau J
Introduction to Experimental Biophysics: Biological Methods for Physical Scientists null
Qiang Wei et al.
ACS biomaterials science & engineering, 6(8), 4687-4701 (2021-01-19)
Hydrogels have been widely explored for the delivery of cells in a variety of regenerative medicine applications due to their ability to mimic both the biochemical and physical cues of cell microniches. For bone regeneration, in particular, stiff hydrogels mimicking



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货号GTIN
717142-1G04061835489664