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Merck
CN

717592

2-氯腺嘌呤

96%

别名:

2-氯-6-氨基嘌呤

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经验公式(希尔记法):
C5H4ClN5
化学文摘社编号:
分子量:
169.57
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
96%
Form:
solid
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InChI

1S/C5H4ClN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1H,(H3,7,8,9,10,11)

SMILES string

Nc1nc(Cl)nc2nc[nH]c12

InChI key

HBJGQJWNMZDFKL-UHFFFAOYSA-N

assay

96%

form

solid

mp

384-389 °C

functional group

chloro

Quality Level

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Kinga Banach et al.
Nucleosides, nucleotides & nucleic acids, 24(5-7), 465-469 (2005-10-27)
A new kinetic model is presented for analysis of experimental data of oxidation process catalyzed by milk xanthine oxidase. The kinetics for two substrates, xanthine and its analog 2-chloroadenine, in a broad pH range (5.8-9.0) are best described by an
Peng Li et al.
Biochemical pharmacology, 79(7), 1015-1024 (2009-11-10)
Since the heterologous tolerance that develops after chronic morphine administration has been proposed to be an adaptive process, it follows that the time course of the change in the cellular components should coincide with the time course of the altered
Laura Willems et al.
Journal of molecular and cellular cardiology, 38(2), 245-256 (2005-02-09)
Aging is associated with reduced tolerance to ischemic insult, and genesis of this intolerant phenotype is poorly understood. We characterized effects of aging and gender on cardiovascular function and cell damage during 20 min ischemia and 60 min reperfusion in
P Hentosh et al.
Nucleic acids research, 19(11), 3143-3148 (1991-06-11)
The purine analog, 2-chloro-2'-deoxyadenosine triphosphate (CldATP), was incorporated enzymatically in place of dATP into the minus strand of M13mp18 duplex DNA. Its effect on protein-DNA interactions was assessed by determining the amount of DNA cleavage by type II restriction endonucleases.
S Lindemalm et al.
Anti-cancer drugs, 8(5), 445-453 (1997-06-01)
Cladribine (2-chloro-2'-deoxyadenosine, CdA) is a purine nucleoside analog with activity against lymphoproliferative and autoimmune disorders. 2-Chloro-2'-arabino-fluoro-2'-deoxyadenosine (CAFdA), a derivative of CdA with better acid stability, shows a similar in vitro spectrum of activity as CdA. 2-Chloroadenine (CAde) is the major

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