质量水平
方案
96%
表单
solid
mp
384-389 °C
官能团
chloro
SMILES字符串
Nc1nc(Cl)nc2nc[nH]c12
InChI
1S/C5H4ClN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1H,(H3,7,8,9,10,11)
InChI key
HBJGQJWNMZDFKL-UHFFFAOYSA-N
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Laura Willems et al.
Journal of molecular and cellular cardiology, 38(2), 245-256 (2005-02-09)
Aging is associated with reduced tolerance to ischemic insult, and genesis of this intolerant phenotype is poorly understood. We characterized effects of aging and gender on cardiovascular function and cell damage during 20 min ischemia and 60 min reperfusion in
P Hentosh et al.
Nucleic acids research, 19(11), 3143-3148 (1991-06-11)
The purine analog, 2-chloro-2'-deoxyadenosine triphosphate (CldATP), was incorporated enzymatically in place of dATP into the minus strand of M13mp18 duplex DNA. Its effect on protein-DNA interactions was assessed by determining the amount of DNA cleavage by type II restriction endonucleases.
Kinga Banach et al.
Nucleosides, nucleotides & nucleic acids, 24(5-7), 465-469 (2005-10-27)
A new kinetic model is presented for analysis of experimental data of oxidation process catalyzed by milk xanthine oxidase. The kinetics for two substrates, xanthine and its analog 2-chloroadenine, in a broad pH range (5.8-9.0) are best described by an
Peng Li et al.
Biochemical pharmacology, 79(7), 1015-1024 (2009-11-10)
Since the heterologous tolerance that develops after chronic morphine administration has been proposed to be an adaptive process, it follows that the time course of the change in the cellular components should coincide with the time course of the altered
P Hentosh et al.
The Biochemical journal, 302 ( Pt 2), 567-571 (1994-09-01)
2-Chloro-2'-deoxyadenosine triphosphate, a purine nucleotide analogue and potent antileukaemic agent, was incorporated into double-stranded 36-mers in place of dATP to investigate the effects of 2-chloroadenine (ClAde) on DNA polymerase-associated 3'-->5' exonuclease activity. ClAde residues within one strand of duplex DNA
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