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Merck
CN

719900

Sigma-Aldrich

Resomer® RG 504 H,聚(D,L-丙交酯-co-乙交酯)

acid terminated, lactide:glycolide 50:50, Mw 38,000-54,000

别名:

RESOMER® RG 504 H, PLGA

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关于此项目

线性分子式:
[C3H4O2]x[C2H2O2]y
化学文摘社编号:
MDL编号:
UNSPSC代码:
12162002
NACRES:
NA.23
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质量水平

表单

amorphous

投料比

lactide:glycolide 50:50

分子量

Mw 38,000-54,000

降解时间线

<3 months

粘度

0.45-0.60 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

转变温度

Tg 46-50 °C

储存温度

2-8°C

SMILES字符串

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key

LCSKNASZPVZHEG-UHFFFAOYSA-N

应用

Resomer® RG 504 H, 聚(D, L-丙交酯-co-乙交酯)可用于制造一种可生物降解的 止血装置,用于安全和局部控制释放凝血酶, 促进局部血栓形成。

它也可用于制备:包封氧化铜的聚合物纳米球,形成刺激响应的多功能纳米载体。

法律信息

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

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商品

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

商业生物材料已停滞不前超过30年的时间,因为很少有材料能够成功地从实验台过渡到临床使用。合成型脂族聚酯因其悠久的历史和获得美国食品药品监督管理局(FDA)批准的记录,一直在可吸收生物材料领域占据主导地位。

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

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