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Merck
CN

719919

Resomer® RG 752 H,聚(D,L-丙交酯-co-乙交酯)

acid terminated, lactide:glycolide 75:25, Mw 4,000-15,000

别名:

RESOMER® RG 752 H, PLGA

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关于此项目

线性分子式:
[C3H4O2]x[C2H2O2]y
化学文摘社编号:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23
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产品名称

Resomer® RG 752 H,聚(D,L-丙交酯-co-乙交酯), acid terminated, lactide:glycolide 75:25, Mw 4,000-15,000

SMILES string

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key

LCSKNASZPVZHEG-UHFFFAOYSA-N

form

(Powder or Solid or Chunk(s))

feed ratio

lactide:glycolide 75:25

mol wt

Mw 4,000-15,000

degradation timeframe

<6 months

impurities

≤0.1% Sulfated Ash (CONF0010 Conforms)

viscosity

0.14-0.22 dL/g, 0.5 % in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

transition temp

Tg 42-46 °C

storage temp.

2-8°C

Quality Level

General description

聚(D, L-丙交酯-co-乙交酯)(PLGA)是一种可生物降解和生物可吸收的聚合物,广泛用于可植入和可注射药物递送系统的配方中。PLGA材料可在体内诱导极小的炎症反应,并降解产生生物相容性乳酸和乙醇酸。

Legal Information

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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商品

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

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