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Merck
CN

719919

Sigma-Aldrich

Resomer® RG 752 H，聚（D,L-丙交酯-co-乙交酯）

acid terminated, lactide:glycolide 75:25, Mw 4,000-15,000

别名:

RESOMER® RG 752 H, PLGA

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关于此项目

线性分子式:
[C3H4O2]x[C2H2O2]y
化学文摘社编号:
26780-50-7
MDL编号:
MFCD00131930
UNSPSC代码:
12162002
NACRES:
NA.23

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质量水平

200

表单

(Powder or Solid or Chunk(s))

投料比

lactide:glycolide 75:25

分子量

Mw 4,000-15,000

降解时间线

<6 months

杂质

≤0.1% Sulfated Ash (CONF0010 Conforms)

粘度

0.14-0.22 dL/g, 0.5 % in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

转变温度

Tg 42-46 °C

储存温度

2-8°C

SMILES字符串

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key

LCSKNASZPVZHEG-UHFFFAOYSA-N

相关类别

一般描述

聚（D, L-丙交酯-co-乙交酯）（PLGA）是一种可生物降解和生物可吸收的聚合物，广泛用于可植入和可注射药物递送系统的配方中。PLGA材料可在体内诱导极小的炎症反应，并降解产生生物相容性乳酸和乙醇酸。

法律信息

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCV6696
BCCH1655
BCCH7543
BCCG6649
BCCG0691

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商品

RESOMER® - Biodegradable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

聚甘油癸二酸酯在组织工程和再生医学的应用

商业生物材料已停滞不前超过30年的时间，因为很少有材料能够成功地从实验台过渡到临床使用。合成型脂族聚酯因其悠久的历史和获得美国食品药品监督管理局（FDA）批准的记录，一直在可吸收生物材料领域占据主导地位。

Poly(Glycerol Sebacate) in Tissue Engineering

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

Biodegradable Polyester Nanoparticle Formation

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

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