721352
3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester
97%
别名:
2-(3,6-Dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C11H19BO3
化学文摘社编号:
分子量:
210.08
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
产品名称
3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester, 97%
InChI
1S/C11H19BO3/c1-10(2)11(3,4)15-12(14-10)9-5-7-13-8-6-9/h5H,6-8H2,1-4H3
SMILES string
CC1(C)OB(OC1(C)C)C2=CCOCC2
InChI key
DOSGEBYQRMBTGS-UHFFFAOYSA-N
assay
97%
form
solid
mp
63-67 °C
functional group
ether
storage temp.
2-8°C
Quality Level
Application
3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester can be used:
- To prepare 1,2-dihydro-2-oxopyridine based endocannabinoid system (ECS) modulators.
- As an intermediate in the synthesis of embryonic ectoderm development (EED) inhibitors.
- To prepare pyrrolotriazine based IRAK4 inhibitors.
Modification on the 1, 2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system
Gado F, et al.
Bioorganic Chemistry, 94, 103353-103353 (2020)
Optimization of permeability in a series of pyrrolotriazine inhibitors of IRAK4
Degorce SL, et al.
Bioorganic & Medicinal Chemistry, 26(4), 913-924 (2018)
EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development
Rej RK, et al.
Journal of medicinal chemistry, 63(13), 7252-7267 (2020)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持