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Merck
CN

723142

三[2-(二甲氨基)乙基]胺

97%

别名:

Me6TREN

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关于此项目

经验公式(希尔记法):
C12H30N4
化学文摘社编号:
分子量:
230.39
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
MDL number:
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产品名称

三[2-(二甲氨基)乙基]胺, 97%

InChI

1S/C12H30N4/c1-13(2)7-10-16(11-8-14(3)4)12-9-15(5)6/h7-12H2,1-6H3

SMILES string

CN(C)CCN(CCN(C)C)CCN(C)C

InChI key

VMGSQCIDWAUGLQ-UHFFFAOYSA-N

assay

97%

form

liquid

refractive index

n20/D 1.455

density

0.862 g/mL at 25 °C

Quality Level

Application

Me6TREN与铜化合物形成络合物,可用作金属酶氧化还原反应中的配体。
用于生产遥爪聚合物的原子转移自由基聚合反应(ATRP)配体。

General description

三[2-(二甲基氨基)乙基]胺(Me6TREN)是形成四齿配体的脂肪族叔胺。这种成分主要用于原子转移自由基聚合(ATRP)。它是(2-氨基乙基)胺的六甲基衍生物,也称为trenMe。可通过修饰Ristempart合成制备这一成分。

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

219.9 °F - closed cup

flash_point_c

104.4 °C - closed cup


历史批次信息供参考:

分析证书(COA)

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Expanding the scope of the photoinduced living radical polymerization of acrylates in the presence of CuBr2 and Me6-Tren
Anastasaki A, et al.
Macromolecules, 47(12), 3852-3859 (2014)
Xiaoli Zhang et al.
Asian journal of pharmaceutical sciences, 15(5), 605-616 (2020-11-17)
Tumor cells show acidic conditions compared with normal cells, which further inspires scientist to build nanocarrier responsive to tumor microenvironment (TME) for enhancing tumor therapeutic efficacy. Here, we report a pH-sensitive and biocompatible polyprodrug based on dextran-doxorubicin (DOX) prodrug (DOXDT)
Tsarevsky, N. V.; Braunecker, W. A.; Brooks, S. J.; Matyjaszewski, K.
Marcromolecules, 39, 6817-6817 (2006)
Xia Song et al.
Biomacromolecules, 17(12), 3957-3963 (2016-10-25)
Paclitaxel (PTX), a hydrophobic anticancer drug, is facing several clinical limitations such as low bioavailability and drug resistance. To solve the problems, a well-defined β-cyclodextrin-poly(N-isopropylacrylamide) star polymer was synthesized and used as a nanocarrier to improve the water solubility and
Diminishing catalyst concentration in atom transfer radical polymerization with reducing agents
Matyjaszewski K, et al.
Proceedings of the National Academy of Sciences of the USA, 103(42), 15309-15314 (2006)

商品

ATRP is a successful method for precise polymer synthesis with controlled molecular weights and high chain end functionalities.

Micro review of reversible addition/fragmentation chain transfer (RAFT) polymerization.

实验方案

We present an article about RAFT, or Reversible Addition/Fragmentation Chain Transfer, which is a form of living radical polymerization.

Polymerization via ATRP procedures demonstrated by Prof. Dave Haddleton's research group at the University of Warwick.

We presents an article featuring procedures that describe polymerization of methyl methacrylate and vinyl acetate homopolymers and a block copolymer as performed by researchers at CSIRO.

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