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Merck
CN

730971

2-(二异丙基氨基)甲基丙烯酸乙酯

97%, contains ~100 ppm monomethyl ether hydroquinone as inhibitor

别名:

DPA, DPAEMA

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关于此项目

经验公式(希尔记法):
C12H23NO2
化学文摘社编号:
分子量:
213.32
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
240-772-8
MDL number:
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Quality Level

assay

97%

form

liquid

contains

~100 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.145

density

0.900 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

CC(C)N(CCOC(=O)C(C)=C)C(C)C

InChI

1S/C12H23NO2/c1-9(2)12(14)15-8-7-13(10(3)4)11(5)6/h10-11H,1,7-8H2,2-6H3

InChI key

SVYHMICYJHWXIN-UHFFFAOYSA-N

General description

2-(二异丙基氨基)甲基丙烯酸乙酯(DPA)是一种甲基丙烯酸类单体,用于制备各种DPA聚合物,包括聚2-(二异丙基氨基)甲基丙烯酸乙酯(PDPA)。PDPA是水溶性聚合物,对pH和温度变化敏感。在低于pKa值(约6.5)的pH下,PDPA会由疏水变为亲水。这种转变是因为它的氨基发生质子化。PDPA聚合物这一独特性质令其十分适合药物递送、基因递送、传感器、表面、膜和色谱等各种各样的应用。

Application

2-(二异丙基氨基)甲基丙烯酸乙酯可用于:
  • 作为单体,用于聚寡乙二醇甲基丙烯酸甲酯(P(OEGMA))和聚2-(二异丙基氨基)甲基丙烯酸乙酯(PDIPAEMA)经RAFT聚合反应合成多重响应性超支化共聚物。获得的聚合物可用于药物递送、基因递送和组织工程。
  • 作为单体合成嵌段共聚物聚乙二醇-b-聚2-(二异丙基氨基)甲基丙烯酸乙酯(PEG-b-PDPAEMA)。这类pH响应型胶束可用于改进细胞内药物递送。DPA单体负责共聚物的pH响应性。


pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

210.0 °F

flash_point_c

98.9 °C



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
730971-100G04061832929224
730971-25G04061832929231