Merck
CN
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文件

730971

Sigma-Aldrich

2-（二异丙基氨基）甲基丙烯酸乙酯

97%, contains ~100 ppm monomethyl ether hydroquinone as inhibitor

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别名:
DPA, DPAEMA
经验公式（希尔记法）:
C12H23NO2
CAS号:
16715-83-6
分子量:
213.32
EC 号:
240-772-8
MDL编号:
MFCD00072647
PubChem化学物质编号:
329764609
NACRES:
NA.23

检测方案

97%

形式

liquid

包含

~100 ppm monomethyl ether hydroquinone as inhibitor

折射率

n20/D 1.145

密度

0.900 g/mL at 25 °C

储存温度

2-8°C

SMILES string

CC(C)N(CCOC(=O)C(C)=C)C(C)C

InChI

1S/C12H23NO2/c1-9(2)12(14)15-8-7-13(10(3)4)11(5)6/h10-11H,1,7-8H2,2-6H3

InChI key

SVYHMICYJHWXIN-UHFFFAOYSA-N

相关类别

一般描述

2-(Diisopropylamino)ethyl methacrylate (DPA) is a methacrylate class of monomer used to prepare various DPA-derived polymers, which includes poly(2-(diisopropylamino)ethyl methacrylate) (PDPA). PDPA is a water-soluble polymer, which exhibits sensitivity to changes in pH and temperature. At pH levels below its pKa value of approximately 6.5, PDPA undergoes a transition from hydrophobic to hydrophilic behavior. This transition is attributed to the protonation of its amino groups. These unique properties of PDPA polymers consequently make them very useful in various applications such as drug delivery, gene delivery, sensors, surfaces, membranes, and chromatography.

应用

2-(Diisopropylamino)ethyl methacrylate can be used:
  • As a monomer in the synthesis of multi-responsive hyperbranched copolymers by combining poly(oligo(ethylene glycol)methyl methacrylate) (P(OEGMA)) and 2-(diisopropylamino)ethyl methacrylate (PDIPAEMA) using RAFT polymerization. These polymers find application in drug delivery, gene delivery and tissue engineering.
  • A monomers in the synthesis of block copolymer poly(ethyleneglycol)-b-poly(2-(diisopropylamino)ethyl methacrylate) (PEG-b-PDPAEMA). These pH-responsive micelles can be used for enhanced intracellular drug delivery. The DPA monomer contributes to the pH-responsive nature of the copolymers.

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险分类

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

210.0 °F

闪点(°C)

98.9 °C

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