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Merck
CN

731765

聚乙二醇甲醚马来酰亚胺

average Mn 2,000, maleimide, methoxy, chemical modification reagent thiol reactive

别名:

PEG 甲醚马来酰亚胺, 甲氧基 PEG 马来酰亚胺

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关于此项目

线性分子式:
CH3O(CH2CH2O)nCH2CH2OC(O)CH2CH2CH2N[C(O)]2CHCH
UNSPSC Code:
12162002
NACRES:
NA.23
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产品名称

聚乙二醇甲醚马来酰亚胺, average Mn 2,000

form

solid

mol wt

average Mn 2,000

reaction suitability

reagent type: chemical modification reagent
reactivity: thiol reactive

mp

48-52 °C

Mw/Mn

<1.1

Ω-end

maleimide

α-end

methoxy

polymer architecture

shape: linear
functionality: monofunctional

Quality Level

Application

聚(乙二醇)甲基醚马来酰亚胺是马来酰亚胺官能化的聚(乙二醇)。由于马来酰亚胺官能化,该材料可用于快速结合含硫醇的生物分子、API或靶向配体。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Karina L Heredia et al.
Macromolecules, 42(7), 2360-2367 (2009-01-01)
In this report we describe a straightforward approach to synthesize polymers with end-groups that bind site-specifically to two different proteins. Telechelic biotin, maleimide poly(N-isopropylacrylamide) (pNIPAAm) was synthesized for the formation of streptavidin (SAv)-bovine serum albumin (BSA) polymer conjugates. Reversible addition-fragmentation

商品

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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