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Merck
CN

739960

Resomer® RG 505，聚（D,L-丙交酯-co-乙交酯）

ester terminated, Mw 54,000-69,000

别名:

PLGA, RESOMER® RG 505

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关于此项目

线性分子式:
[C3H4O2]x[C2H2O2]y
化学文摘社编号:
26780-50-7
MDL number:
MFCD00131930
UNSPSC Code:
12162002
NACRES:
NA.23

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产品名称

Resomer® RG 505，聚（D,L-丙交酯-co-乙交酯）, ester terminated, Mw 54,000-69,000

SMILES string

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key

LCSKNASZPVZHEG-UHFFFAOYSA-N

form

amorphous

feed ratio

lactide:glycolide 50:50

mol wt

Mw 54,000-69,000

degradation timeframe

<3 months

viscosity

0.61-0.74 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

transition temp

Tg 48-52 °C

storage temp.

2-8°C

Quality Level

100

相关类别

Application

聚 （丙交酯-乙交酯）（PLGA）可用于制造缓释药物递送体系，例如，它可用于包裹抗炎亲脂药物阿托伐他汀。

General description

聚 （丙交酯-乙交酯）（PLGA）是一种可生物降解的聚合物，用于制备聚合物微球。这些聚合物在体内通过其酯骨架水解为无毒产物而降解，这些无毒产物可由肾脏排出，或通过生物化学途径分解为CO2 和水。PLGA微球被广泛应用于包裹药物分子，并可用作长效缓释药物制剂。

Legal Information

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SDBB3928
SDBB0464
STBL2290
STBK8649
STBK5207

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