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Merck
CN

752460

聚乙二醇双(胺)

average MN 10,000, cross-linking reagent carboxyl reactive, amine

别名:

O,O′-双(2-氨基乙基)聚乙二醇, 二氨基聚乙二醇, 聚乙二醇二胺, 聚氧乙烯二胺

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关于此项目

线性分子式:
H2N(CH2CH2O)nCH2CH2NH2
化学文摘社编号:
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
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产品名称

聚乙二醇双(胺), average Mn 10,000

SMILES string

NCCOCCOCCN

InChI

1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2

InChI key

IWBOPFCKHIJFMS-UHFFFAOYSA-N

form

powder or solid (or chunk(s))

mol wt

average Mn 10,000

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

mp

56-60 °C

Ω-end

amine

α-end

amine

polymer architecture

shape: linear
functionality: homobifunctional

Quality Level

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Application

Polymer for preparing enzyme conjugates soluble in organic solvents†; promising drug carrier†

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Malar A. Azagarsamy, et al.
Material Matters, 7 (2012)
Takahiko Matsushita et al.
The Journal of organic chemistry, 71(8), 3051-3063 (2006-04-08)
A MUC1-related glycopeptide having five core-2 hexasaccharide branches (C330H527N46O207, MW = 8450.9) was synthesized by a new strategy using a combination of microwave-assisted solid-phase synthesis (MA-SPGS) and enzymatic sugar elongation. Synthesis of a key glycopeptide intermediate was best achieved in
Phaedria M St Hilaire et al.
Journal of medicinal chemistry, 45(10), 1971-1982 (2002-05-03)
A one-bead-two-compound inhibitor library was synthesized by the split-mix method for the identification of inhibitors of a recombinant cysteine protease from Leishmania mexicana, CPB2.8DeltaCTE. The inhibitor library was composed of octapeptides with a centrally located reduced bond introduced by reductive
Alison G Patrick et al.
Macromolecular bioscience, 10(10), 1184-1193 (2010-07-02)
The design of hydrogels that simultaneously report protease activity and remove excess protease from solution is elucidated. The hydrogels, based on amino-PEGA, combine enzyme-specific peptides flanked with FRET complimented by charged amino acid residues that facilitate protease uptake via short
Stephen J Connon et al.
Bioorganic & medicinal chemistry letters, 12(14), 1873-1876 (2002-06-28)
The synthesis and olefin metathesis activity in protic solvents of 7, a phosphine-free ruthenium alkylidene bound to a hydrophilic solid support are reported. This heterogeneous catalyst promotes relatively efficient ring closing- and cross-metathesis reactions in both methanol and water. The

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Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

将基于水凝胶的生物材料用于递送和募集细胞以促进体内组织再生是新生的研究热题。本文讨论了水凝胶在细胞递送和组织再生中的应用。

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