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Merck
CN

764620

Sigma-Aldrich

Poly(D,L-lactide)

greener alternative

average Mn 10,000, PDI ≤1.4

别名:

PDLA, PLA, polyDL-lactide

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关于此项目

UNSPSC代码:
12162002
NACRES:
NA.23
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表单

solid

旋光性

[α]/D 0°, c = 0.5% in chloroform

分子量

average Mn 10,000

环保替代产品特性

Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

降解时间线

<6 months

mp

287-293 °C

PDI

≤1.4

环保替代产品分类

储存温度

2-8°C

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一般描述

We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This is an enabling product that belongs to a family of high-performance bio-based polymers that are essential for developing efficient, low-cost, and environmentally friendly renewable energy solutions. Click here for more information.

应用

Used in Drug Delivery including coating nanoparticles1. Can be end-group functionalizated2 or used as a macroinitiator/block precursor3.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

商品

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

商业生物材料已停滞不前超过30年的时间,因为很少有材料能够成功地从实验台过渡到临床使用。合成型脂族聚酯因其悠久的历史和获得美国食品药品监督管理局(FDA)批准的记录,一直在可吸收生物材料领域占据主导地位。

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

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