描述
typical PEG PDI<1.1; overall PDI<1.2 (THF, PEO)
表单
liquid
投料比
lactide:glycolide 50:50
分子量
PEG average Mn 1,000
PLGA average Mn 2000
average Mn (1,000-1,000-1,000)
降解时间线
1-2 weeks
PDI
<1.2
储存温度
2-8°C
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一般描述
PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.
应用
Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.
特点和优势
Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified.
储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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