主要文件

764787

Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)

Name: Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)
Brand: ALDRICH

average M_n (1,000-1,000-1,000), lactide:glycolide 50:50

别名:

PLGA-PEG-PLGA

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关于此项目

NACRES:

NA.23

UNSPSC Code:

12162002

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属性

description

typical PEG PDI<1.1; overall PDI<1.2 (THF, PEO)

form

liquid

feed ratio

lactide:glycolide 50:50

mol wt

PEG average M_n 1,000, PLGA average M_n 2000, average M_n (1,000-1,000-1,000)

degradation timeframe

1-2 weeks

PDI

<1.2

storage temp.

2-8°C

说明

General description

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Features and Benefits

Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified.

存储类别

10 - Combustible liquids

怎么回事？

nwg

闪点 (F)

Not applicable

闪点 (°C)

Not applicable

历史批次信息供参考:

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