主要文件

764817

Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)

Name: Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)
Brand: ALDRICH

average M_n (1100-1000-1100), lactide:glycolide 75:25

别名:

PLGA-PEG-PLGA

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关于此项目

NACRES:

NA.23

UNSPSC Code:

12162002

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属性

description

typical PEG PDI<1.1; overall PDI≤2.0 (THF, PS)

Quality Segment

100

form

semisolid

feed ratio

lactide:glycolide 75:25

mol wt

PEG average M_n 1,000, PLGA average M_n 2,200, average M_n (1100-1000-1100)

degradation timeframe

2-3 weeks

transition temp

T_m 230-235 °C

PDI

<2.0

storage temp.

2-8°C

说明

General description

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Features and Benefits

Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified.

Legal Information

Product of AKINA, Inc.

存储类别

11 - Combustible Solids

怎么回事？

WGK 3

闪点 (F)

Not applicable

闪点 (°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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