2- {2- [2-（2-巯基乙氧基）乙氧基]乙氧基}乙醇

Name: 2- {2- [2-（2-巯基乙氧基）乙氧基]乙氧基}乙醇
Brand: ALDRICH

97%

别名:

MEEE, 1-Mercapto-11-hydroxy-3,6,9-trioxaundecane

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关于此项目

经验公式（希尔记法）:

C₈H₁₈O₄S

分子量:

210.29

NACRES:

NA.22

PubChem Substance ID:

329767336

UNSPSC Code:

12352200

MDL number:

MFCD22574773

Assay:

97%

Form:

liquid

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属性

Quality Level

100

assay

97%

form

liquid

reaction suitability

reagent type: cross-linking reagent

refractive index

n20/D 1.481

density

1.098 g/mL at 25 °C

SMILES string

OCCOCCOCCOCCS

InChI

1S/C8H18O4S/c9-1-2-10-3-4-11-5-6-12-7-8-13/h9,13H,1-8H2

InChI key

GKKYNULPAQDGHI-UHFFFAOYSA-N

说明

Application

2-{2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy}ethanol may be used in the synthesis of 2-(2-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)ethoxy)ethoxy)ethanol, an nitrobenzoxadiazole (NBD) analog of the anticancer agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX). This analog is a potent glutathione S-transferase (GST) and a potential therapeutic antimelanoma agent with enhanced water solubility and antitumor efficacy when compared to NBDHEX in a study.

Oligo-ehtylene glycol of peptides and small molecules (PEGylation)
PEG-disulfide formation
ultra-thin protein-resistant monolayers
Densely packed monolayer and a flexible-hydrophilic oligo ethylene glycol arm for avoiding non-specific adsorption