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Merck
CN

803588

BM(PEG)2 (1,8-双马来酰亚胺基-二甘醇)

别名:

1,2-Bis(2-maleimidoethoxy)ethane, 1,8-Bis(maleimido)-3,6-dioxaoctane

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关于此项目

经验公式(希尔记法):
C14H16N2O6
化学文摘社编号:
分子量:
308.29
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥90%
Form:
powder
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InChI

1S/C14H16N2O6/c17-11-1-2-12(18)15(11)5-7-21-9-10-22-8-6-16-13(19)3-4-14(16)20/h1-4H,5-10H2

SMILES string

O=C(C=CC1=O)N1CCOCCOCCN2C(C=CC2=O)=O

InChI key

FERLGYOHRKHQJP-UHFFFAOYSA-N

assay

≥90%

form

powder

mol wt

308.29

reaction suitability

reagent type: cross-linking reagent

storage condition

desiccated

solubility

water: soluble

shipped in

ambient

storage temp.

2-8°C

General description

BM(PEG)2和BM(PEG)3是同双功能马来酰亚胺交联剂,用于巯基(-SH)之间的缀合。此类双马来酰亚胺交联剂通常用于探索和表征蛋白质结构(即寡聚化)或蛋白质相互作用。由于BM(PEG)2和BM(PEG)3具有相同的反应性,但长度不同,因此这些试剂和类似试剂在蛋白质低聚物位点之间形成交联或相互作用方面的相对成功可以帮助确定分子内和分子间的距离。

Features and Benefits

  • 反应基团:马来酰亚胺(两端)
  • 反应性基团:巯基
  • 长聚乙二醇化巯基-巯基交联剂,由马来酰亚胺基团和2-单元聚乙二醇间隔臂组成
  • PEG间隔臂提供独特的优势,包括增加溶解度、增加稳定性、降低聚集倾向和降低免疫原性
  • 具有确定结构和分子量的纯化合物,确保可重复的蛋白质修饰效果
  • 非常适合小分子或肽结合

Disclaimer

本品对水分敏感。小瓶包装在具有干燥剂的可重新密封袋中,以减少水分暴露。冷藏后,打开前将小瓶平衡至室温,以减少小瓶内的冷凝。制作新鲜溶液。不建议储存储备液。使用后,将小瓶放回可重新密封的袋中。关闭袋子并将产品存放在建议的温度下。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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