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Merck
CN

807761

palmitic-acid-5-hydroxy-stearic-acid

95%

别名:

5-PAHSA

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关于此项目

经验公式(希尔记法):
C34H66O4
化学文摘社编号:
分子量:
538.89
MDL number:
NACRES:
NA.22
UNSPSC Code:
12352106
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Quality Segment

assay

95%

form

powder

mp

39 °C

storage temp.

2-8°C

General description

Palmitic-acid-5-hydroxy-stearic-acid (5-PAHSA) is also referred to as 5-hexadecanoyloxyoctadecanoic acid (IUPAC name).

Application

5-PAHSA is composed of palmitic acid attached to stearic acid and is in the class of branched lipids referred to as fatty acid esters of hydroxy fatty acids (FAHFAs). 5-PAHSA was found at reduced levels in adipose tissue and serum of insulin-resistant mice. Levels were also found to be lower in white adipose tissue and serum of humans. Studies of oral administration of 5-PAHSA to obese, diabetic mice showed improved glucose tolerance. In characterizing the mechanism, it was found that 5-PAHSA stimulates insulin and GLP-1 secretion and also enhances glucose transport and the Glut4 transporter through activation of GPR-120.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

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