InChI key
PCHJSUWPFVWCPO-UHFFFAOYSA-N
InChI
1S/Au
material
PEG 5000
form
dispersion in H2O, nanoparticles
composition
, 2.99E+14 particles/mL
packaging
pkg of 0.5 mL
concentration
3.04 mg/mL in H2O
OD
50
surface area
30.8 m2/g
diameter
10 nm
pH
5-7
density
1.00 g/cm3
λmax
515-520 nm
functional group
biotin
storage temp.
2-8°C
Quality Level
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General description
Gold nanoparticles PEG 5000 biotin terminated.
Application
Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent, and ranges from 515-520 nm for a 5 nm particle to 572 nm for a 100 nm particle.
Gold nanoparticles 10 nm diameter, biotin terminated, PEG 5000, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.
Legal Information
Product of Cytodiagnostics, Inc.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy
Heo DN, et al.
Biomaterials, 33(3), 856-866 (2012)
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 33(6), 666-680 (2020)
Colorimetric biosensing of pathogenss using gold nanoparticles
Verma MS, et al.
Biotechnology Advances, 33(6), 666-680 (2015)
Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patients
Itani R, et al.
Theranostics, 10(13), 5932-5932 (2020)
Localized surface plasmon resonance (LSPR) of polyelectrolyte-functionalized gold-nanoparticles for bio-sensing
Li X, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 332(2-3), 172-179 (2009)
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