物料
PEG 5000
质量水平
表单
dispersion in H2O
nanoparticles
组成
, 3.58E12 particles/mL
包装
pkg of 0.5 mL
储存条件
do not freeze
浓度
2.33 mg/mL in H2O
OD
50
表面积
7.74 m2/g
直径
40 nm
pH值（酸碱度）
5-7
密度
1.00 g/cm3
peak SPR wavelength
530 nm
官能团
biotin
储存温度
2-8°C
InChI
1S/Au
InChI key
PCHJSUWPFVWCPO-UHFFFAOYSA-N
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一般描述
Gold nanoparticles PEG 5000 biotin terminated.The preparation of biotinylated gold nanoparticles involves two surface modification steps. First the carboxyl-terminated alkanethiol is attached to the surface of gold nanoparticles via chemisorption in the presence of a stabilizing agent. This step is followed by the reaction of the carboxyl groups with (+)-biotinyl-3,6,9,-trioxaundecanediamine and 2-(2-aminoethoxy)ethanol.
应用
Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent and ranges from 515-520nm for a 5nm particle to 572nm for a 100nm particle.
Gold nanoparticles 40 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.
法律信息
Product of CytoDiagnostics, Inc.
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Controlled and reversible aggregation of biotinylated gold nanoparticles with streptavidin.
Aslan K, et al.
The Journal of Physical Chemistry B, 108(40), 15631-15639 (2004)
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Li X, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 332(2-3), 172-179 (2009)
Colorimetric biosensing of pathogenss using gold nanoparticles
Verma MS, et al.
Biotechnology Advances, 33(6), 666-680 (2015)
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