InChI
1S/Au
InChI key
PCHJSUWPFVWCPO-UHFFFAOYSA-N
material
PEG 5000
form
dispersion in H2O, nanoparticles
composition
, 1.92E11 particles/mL
packaging
pkg of 0.5 mL
storage condition
do not freeze
concentration
3.89E-02 mg/mL W
OD
50
surface area
3.08 m2/g
diameter
100 nm
pH
5-7
density
1.00 g/cm3
λmax
572 nm
functional group
biotin
storage temp.
2-8°C
Quality Level
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General description
Concentrations is indicated at an optical density of 1 (OD=1, i.e. absorbance at peak SPR wavelength with a 1cm pathlength)
Gold nanoparticles PEG 5000 biotin terminated.The preparation of biotinylated gold nanoparticles involves two surface modification steps. First, the carboxyl-terminated alkanethiol is attached to the surface of gold nanoparticles via chemisorption in the presence of a stabilizing agent. This step is followed by the reaction of the carboxyl groups with (+)-biotinyl-3,6,9,-trioxaundecanediamine and 2-(2-aminoethoxy)ethanol.
Application
Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent and ranges from 515-520nm for a 5nm particle to 572nm for a 100nm particle.
Gold nanoparticles 100 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.
Legal Information
Product of CytoDiagnostics, Inc.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
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