83060
12-氨基-4,7,10-三氧杂十二烷酸叔丁酯
technical, ≥80% (T)
别名:
3-[2-(2-(2-氨基乙氧基)乙氧基)乙氧基]丙酸叔丁酯
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C13H27NO5
化学文摘社编号:
分子量:
277.36
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥80% (T)
Form:
solid
InChI key
CWFSAZJIJBTKRC-UHFFFAOYSA-N
SMILES string
CC(C)(C)OC(=O)CCOCCOCCOCCN
InChI
1S/C13H27NO5/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h4-11,14H2,1-3H3
grade
technical
assay
≥80% (T)
form
solid
reaction suitability
reagent type: cross-linking reagent
storage temp.
−20°C
Quality Level
Application
tert-Butyl 12-amino-4,7,10-trioxadodecanoate is generally used as a spacer or linker in bioconjugate chemistry. Some of its applications are:
- Synthesis of the tetanus-toxin conjugate of MUC1 glycopeptide antigen, as a potential antitumor vaccine.
- Synthesis of self-assembled monolayer-based surface-enhanced raman scattering (SERS) labels for immuno-SERS microscopy.
- Synthesis of polycationic adamantane-based dendrons for cell imaging.
- Synthesis of phthalocyanine (Pc)-peptide conjugates as potential fluorescence imaging agents for cancers overexpressing epidermal growth factor receptors (EGFR).
Other Notes
合成组合化学所用间隔臂的中间体
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
337.5 °F
flash_point_c
169.7 °C
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Towards the Development of Antitumor Vaccines: A Synthetic Conjugate of a Tumor?Associated MUC1 Glycopeptide Antigen and a Tetanus Toxin Epitope.
Keil S, et al.
Angewandte Chemie (International Edition in English), 40(2), 366-369 (2001)
Phthalocyanine?peptide conjugates for epidermal growth factor receptor targeting.
Ongarora B G, et al.
Journal of Medicinal Chemistry, 55(8), 3725-3738 (2012)
Polycationic adamantane-based dendrons of different generations display high cellular uptake without triggering cytotoxicity.
Grillaud M, et al.
Journal of the American Chemical Society, 136(2), 810-819 (2014)
Water soluble SERS labels comprising a SAM with dual spacers for controlled bioconjugation.
Jehn C, et al.
Physical Chemistry Chemical Physics, 11(34), 7499-7504 (2009)
Angewandte Chemie (International Edition in English), 113, 379-379 (2001)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持