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850217

3,4-二羟基苯乙酸

Name: 3,4-二羟基苯乙酸
Brand: ALDRICH

98%

别名:

DOPAC, 高原儿茶酸

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关于此项目

线性分子式:

(HO)₂C₆H₃CH₂CO₂H

化学文摘社编号:

102-32-9

分子量:

168.15

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24888293

EC Number:

203-024-1

Beilstein/REAXYS Number:

2211017

MDL number:

MFCD00004338

Assay:

98%

Form:

powder

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属性

Quality Level

100

assay

98%

form

powder

mp

127-130 °C (lit.)

solubility

water: soluble 50 mg/mL, clear, almost colorless

functional group

carboxylic acid

SMILES string

OC(=O)Cc1ccc(O)c(O)c1

InChI

1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)

InChI key

CFFZDZCDUFSOFZ-UHFFFAOYSA-N

说明

General description

3，4-二羟基苯乙酸（DOPAC）是大鼠脑组织的正常成分。已经描述了用于测定大鼠脑组织中二羟苯乙酸的质量碎片法。它是多巴胺（DA）的主要代谢产物。在用单壁碳纳米管（SWNT）改性的玻碳电极上研究了二羟苯乙酸的伏安还原。已经报道了用于二羟苯乙酸的半自动荧光测定技术。

Application

3，4-二羟基苯乙酸可用作制备 Mo（VI）配合物的配体。

Other Notes

2024年CiteAb奖，授予在帕金森研究方面取得成功的供应商

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319

pcodes

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Regional rat brain levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid: concurrent fluorometric measurement and influence of drugs.

B H Westerink et al.

European journal of pharmacology, 38(2), 281-291 (1976-08-01)

A concurrent semi-automatic fluorometric assay technique for 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), is described. The method is based on a rapid manually performed isolation of DOPAC and HVA on small columns of Sephadex G-10 followed by an automated

Footshock and conditioned stress increase 3,4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra.

A Y Deutch et al.

Brain research, 333(1), 143-146 (1985-04-29)

The effects of stress on dopamine (DA) metabolism in the mesencephalic DA cell body areas and DA terminal field regions were examined. Both mild footshock stress and exposure to a neutral stimulus previously paired with footshock resulted in a selective

Simultaneous mass fragmentographic determination of 3, 4-dihydroxyphenylacetic acid and 4 hydroxy-3-methoxyphenylacetic acid in brain tissue.

F A Wiesel et al.

Journal of neural transmission, 35(4), 319-326 (1974-01-01)

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全球贸易项目编号

货号	GTIN
850217-5G	04061833014790
850217-1G	04061833014783