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Merck
CN

852228

2′-脱氧鸟苷5′-单磷酸 二钠盐 水合物

≥98%

别名:

5′-dGMP 二钠盐

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关于此项目

经验公式(希尔记法):
C10H12N5Na2O7P · xH2O
化学文摘社编号:
分子量:
391.18 (anhydrous basis)
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.22
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质量水平

方案

≥98%

表单

solid

杂质

≤4% ethanol

mp

>245 °C (dec.) (lit.)

SMILES字符串

[Na+].[Na+].[H]O[H].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP([O-])([O-])=O)O3)C(=O)N1

InChI

1S/C10H14N5O7P.2Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;;1H2/q;2*+1;/p-2/t4-,5+,6+;;;/m0.../s1

InChI key

HQSJCEYJAGVPJG-BIHLCPNHSA-L

应用

作为反应物,参与以下反应:
  • 溶液中自组装和G-四链体成核/生长分析
  • 亲核捕集
  • 还原性烷化

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Shweta Singh et al.
Physical chemistry chemical physics : PCCP, 14(41), 14315-14324 (2012-09-26)
In order to gain insights into nucleotide-protein interaction, the molecular interaction of glycine (Gly) with 2'-deoxyguanosine 5'-monophosphate (dGMP) was monitored in aqueous media through Raman spectroscopic measurements and density functional theory (DFT) calculations. Raman spectra of dGMP, glycine and their
Mariana P Serrano et al.
Physical chemistry chemical physics : PCCP, 14(33), 11657-11665 (2012-07-25)
UV-A radiation (320-400 nm) induces damage to the DNA molecule and its components through photosensitized reactions. Biopterin (Bip) and its photoproducts 6-formylpterin (Fop) and 6-carboxypterin (Cap) accumulate in the skin of human beings suffering from vitiligo, a depigmentation disorder where
Jean L Whittingham et al.
The Biochemical journal, 428(3), 499-509 (2010-04-01)
Plasmodium falciparum is the causative agent of malaria, a disease where new drug targets are required due to increasing resistance to current anti-malarials. TMPK (thymidylate kinase) is a good candidate as it is essential for the synthesis of dTTP, a
Alireza Ariafard et al.
Inorganic chemistry, 52(2), 707-717 (2012-12-29)
The mechanism for the oxidation of 3'-dGMP by [PtCl(4)(dach)] (dach = diaminocyclohexane) in the presence of [PtCl(2)(dach)] has been investigated using density functional theory. We find that the initial complexation, i.e., the formation of [PtCl(3)(dach)(3'-dGMP)], is greatly assisted by the
Yancheng Liu et al.
Journal of photochemistry and photobiology. B, Biology, 118, 58-65 (2012-12-12)
Photochemical properties and phototoxicity of Pazufloxacin (PAX) were systematically investigated in aqueous solutions using UV-Vis, fluorescence, laser flash photolysis, pulse radiolysis and SDS-PAGE gel electrophoresis techniques. PAX triplet-state ((3)PAX(*)) absorption spectra (λ(max)=570 nm) was determined. (3)PAX(*) was quenched by PAX

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