852228
2′-脱氧鸟苷5′-单磷酸 二钠盐 水合物
≥98%
别名:
5′-dGMP 二钠盐
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关于此项目
经验公式（希尔记法）:
C10H12N5Na2O7P · xH2O
化学文摘社编号:
分子量:
391.18 (anhydrous basis)
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
≥98%
表单
solid
杂质
≤4% ethanol
mp
>245 °C (dec.) (lit.)
SMILES字符串
[Na+].[Na+].[H]O[H].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP([O-])([O-])=O)O3)C(=O)N1
InChI
1S/C10H14N5O7P.2Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;;1H2/q;2*+1;/p-2/t4-,5+,6+;;;/m0.../s1
InChI key
HQSJCEYJAGVPJG-BIHLCPNHSA-L
应用
作为反应物，参与以下反应：
- 溶液中自组装和G-四链体成核/生长分析
- 亲核捕集
- 还原性烷化
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Mariana P Serrano et al.
Physical chemistry chemical physics : PCCP, 14(33), 11657-11665 (2012-07-25)
UV-A radiation (320-400 nm) induces damage to the DNA molecule and its components through photosensitized reactions. Biopterin (Bip) and its photoproducts 6-formylpterin (Fop) and 6-carboxypterin (Cap) accumulate in the skin of human beings suffering from vitiligo, a depigmentation disorder where
Shweta Singh et al.
Physical chemistry chemical physics : PCCP, 14(41), 14315-14324 (2012-09-26)
In order to gain insights into nucleotide-protein interaction, the molecular interaction of glycine (Gly) with 2'-deoxyguanosine 5'-monophosphate (dGMP) was monitored in aqueous media through Raman spectroscopic measurements and density functional theory (DFT) calculations. Raman spectra of dGMP, glycine and their
Mahmoud Kandeel et al.
Nucleic acids symposium series (2004), (53)(53), 39-40 (2009-09-15)
In Plasmodium falciparum, deoxyguanylate was found to be a substrate for several DNA metabolizing enzymes. Guanylate kinase utilizes dGMP with very low specificity, which is estimated to be the lowest among well-known prokaryotic and eukaryotic enzymes. Furthermore, thymidylate kinase, which
Jean L Whittingham et al.
The Biochemical journal, 428(3), 499-509 (2010-04-01)
Plasmodium falciparum is the causative agent of malaria, a disease where new drug targets are required due to increasing resistance to current anti-malarials. TMPK (thymidylate kinase) is a good candidate as it is essential for the synthesis of dTTP, a
Mingfeng Li et al.
PloS one, 8(1), e54420-e54420 (2013-02-01)
Free extracellular DNA provides nutrition to bacteria and promotes bacterial evolution by inducing excessive mutagenesis of the genome. To understand the influence of extracellular DNA fragments on D. radiodurans, we investigated cell growth and survival after extracellular DNA or dNMPs
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