852228
2′-脱氧鸟苷5′-单磷酸 二钠盐 水合物
≥98%
别名:
5′-dGMP 二钠盐
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关于此项目
经验公式（希尔记法）:
C10H12N5Na2O7P · xH2O
化学文摘社编号:
分子量:
391.18 (anhydrous basis)
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Assay:
≥98%
Form:
solid
Quality Level
assay
≥98%
form
solid
impurities
≤4% ethanol
mp
>245 °C (dec.) (lit.)
SMILES string
[Na+].[Na+].[H]O[H].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP([O-])([O-])=O)O3)C(=O)N1
InChI
1S/C10H14N5O7P.2Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;;1H2/q;2*+1;/p-2/t4-,5+,6+;;;/m0.../s1
InChI key
HQSJCEYJAGVPJG-BIHLCPNHSA-L
Application
作为反应物，参与以下反应：
- 溶液中自组装和G-四链体成核/生长分析
- 亲核捕集
- 还原性烷化
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Jean L Whittingham et al.
The Biochemical journal, 428(3), 499-509 (2010-04-01)
Plasmodium falciparum is the causative agent of malaria, a disease where new drug targets are required due to increasing resistance to current anti-malarials. TMPK (thymidylate kinase) is a good candidate as it is essential for the synthesis of dTTP, a
Mahmoud Kandeel et al.
Nucleic acids symposium series (2004), (53)(53), 39-40 (2009-09-15)
In Plasmodium falciparum, deoxyguanylate was found to be a substrate for several DNA metabolizing enzymes. Guanylate kinase utilizes dGMP with very low specificity, which is estimated to be the lowest among well-known prokaryotic and eukaryotic enzymes. Furthermore, thymidylate kinase, which
Mariko Higuchi et al.
Journal of structural biology, 173(1), 20-28 (2010-10-05)
MutT distinguishes substrate 8-oxo-dGTP from dGTP and also 8-oxo-dGMP from dGMP despite small differences of chemical structures between them. In this paper we show by the method of molecular dynamics simulation that the transition between conformational substates of MutT is
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 852228-1G | 04061826708095 |