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Merck
CN

852481

6-氯嘌呤核苷

99%

别名:

6-氯嘌呤-9-β-D-呋喃核糖苷

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关于此项目

经验公式(希尔记法):
C10H11ClN4O4
化学文摘社编号:
分子量:
286.67
UNSPSC Code:
12352123
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-438-4
Beilstein/REAXYS Number:
40573
MDL number:
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Quality Level

assay

99%

form

powder

mp

158-162 °C (dec.) (lit.)

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(Cl)ncnc23

InChI

1S/C10H11ClN4O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2/t4-,6-,7-,10-/m1/s1

InChI key

XHRJGHCQQPETRH-KQYNXXCUSA-N

Application

关于这种核苷的地球化学和生物效应的综述,请参见 Adv. Exp. Med. Biol.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

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Chem. Abstr., 106, 95594r-95594r (1987)
Cintia W Rivero et al.
Bioorganic & medicinal chemistry letters, 22(19), 6059-6062 (2012-09-11)
This work describes the application of thermophilic microorganisms for obtaining 6-halogenated purine nucleosides. Biosynthesis of 6-chloropurine-2'-deoxyriboside and 6-chloropurine riboside was achieved by Geobacillus stearothermophilus CECT 43 with a conversion of 90% and 68%, respectively. Furthermore, the selected microorganism was satisfactorily
Shigetada Kozai et al.
Nucleosides, nucleotides & nucleic acids, 22(5-8), 779-781 (2003-10-21)
A new method to introduce a benzyl group onto the 2'-OH of purine ribonucleoside is described. Thus, 6-chloropurine 3'-O-benzoylriboside and its 5'-O-trityl congener were condensed with benzyl alcohol using the Mitsunobu reaction to give the 2'-O-benzyl derivative. The yields were



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货号GTIN
852481-5G04061833315217
852481-1G04061826664902