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经验公式(希尔记法):
C14H14N2O
化学文摘社编号:
分子量:
226.27
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-206-2
Beilstein/REAXYS Number:
163023
MDL number:
Assay:
96%
Form:
powder
产品名称
2-甲基-1,2-二-3-吡啶基-1-丙酮, 96%
InChI key
FJLBFSROUSIWMA-UHFFFAOYSA-N
InChI
1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3
SMILES string
CC(C)(c1cccnc1)C(=O)c2cccnc2
assay
96%
form
powder
mp
52-55 °C (lit.)
functional group
ketone
Quality Level
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Application
2-甲基-1,2-二-3-吡啶基-1-丙酮通过阻断脱氧皮质酮向皮质酮的转化而抑制皮质酮的生物合成。 它广泛用于肾上腺皮质相关的临床研究。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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The Journal of experimental biology, 220(Pt 6), 1056-1064 (2017-01-14)
The zebrafish (Danio rerio) has become a well-established experimental model in many research fields but the loss of the primary sex-determining region during the process of domestication renders laboratory strains of zebrafish susceptible to the effects of environmental factors on
The relationship between adrenocortical function and Hsp70 expression in socially isolated Japanese quail.
Soleimani AF, et al.
Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, 161(2), 140-144 (2012)
Secretion of cortisol and aldosterone as a vulnerable target for adrenal endocrine disruption?screening of 30 selected chemicals in the human H295R cell model.
Uller?s E, et al.
Journal of Applied Toxicology, 28(8), 1045-1053 (2008)
Tamara M Rodela et al.
The Journal of experimental biology, 215(Pt 2), 314-323 (2011-12-23)
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