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Merck
CN

856525

2-甲基-1,2-二-3-吡啶基-1-丙酮

96%

别名:

Su-4885, 美替拉酮

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关于此项目

经验公式(希尔记法):
C14H14N2O
化学文摘社编号:
分子量:
226.27
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-206-2
Beilstein/REAXYS Number:
163023
MDL number:
Assay:
96%
Form:
powder
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产品名称

2-甲基-1,2-二-3-吡啶基-1-丙酮, 96%

InChI key

FJLBFSROUSIWMA-UHFFFAOYSA-N

InChI

1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3

SMILES string

CC(C)(c1cccnc1)C(=O)c2cccnc2

assay

96%

form

powder

mp

52-55 °C (lit.)

functional group

ketone

Quality Level

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Application

2-甲基-1,2-二-3-吡啶基-1-丙酮通过阻断脱氧皮质酮向皮质酮的转化而抑制皮质酮的生物合成。 它广泛用于肾上腺皮质相关的临床研究。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Screening for modulatory effects on steroidogenesis using the human H295R adrenocortical cell line: a metabolomics approach.
Rijk JCW, et al.
Chemical Research in Toxicology, 25(8), 1720-1731 (2012)
Laia Ribas et al.
The Journal of experimental biology, 220(Pt 6), 1056-1064 (2017-01-14)
The zebrafish (Danio rerio) has become a well-established experimental model in many research fields but the loss of the primary sex-determining region during the process of domestication renders laboratory strains of zebrafish susceptible to the effects of environmental factors on
The relationship between adrenocortical function and Hsp70 expression in socially isolated Japanese quail.
Soleimani AF, et al.
Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, 161(2), 140-144 (2012)
Secretion of cortisol and aldosterone as a vulnerable target for adrenal endocrine disruption?screening of 30 selected chemicals in the human H295R cell model.
Uller?s E, et al.
Journal of Applied Toxicology, 28(8), 1045-1053 (2008)
Tamara M Rodela et al.
The Journal of experimental biology, 215(Pt 2), 314-323 (2011-12-23)
In their native environment, gulf toadfish excrete equal quantities of ammonia and urea. However, upon exposure to stressful conditions in the laboratory (i.e. crowding, confinement or air exposure), toadfish decrease branchial ammonia excretion and become ureotelic. The objective of this

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