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Merck
CN

86870

Sigma-Aldrich

四丁基氯化铵

greener alternative

≥97.0% (NT)

别名:

N,N,N-tributyl-butanaminium chloride

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About This Item

线性分子式:
[CH3(CH2)3]4NCl
CAS号:
分子量:
277.92
Beilstein:
3571227
EC 号:
MDL编号:
UNSPSC代码:
12352107
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

≥97.0% (NT)

表单

crystals

环保替代产品特性

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

杂质

≤1% water

溶解性

H2O: 20 mg/mL, clear, colorless

环保替代产品分类

SMILES字符串

[Cl-].CCCC[N+](CCCC)(CCCC)CCCC

InChI

1S/C16H36N.ClH/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;/h5-16H2,1-4H3;1H/q+1;/p-1

InChI key

NHGXDBSUJJNIRV-UHFFFAOYSA-M

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一般描述

四丁基氯化铵是一种季铵盐,通常用作相转移催化剂以及有机合成中的氯离子源。

我们致力于为您带来更环保的替代产品,以符合绿色化学 12 项原则的一项或多项原则要求该产品为增强型,提高了能源效率。点击此处,查看更多详情。

应用

四丁基氯化铵 (TBACl) 可用作相转移催化剂用于合成:
  • 2-氨基-4H-色烯衍生物,通过醛、丙二腈 和 α或 β-萘酚缩合反应制备。
  • 甲酯,通过羧酸和碳酸二甲酯在K2CO3参与下的酯化反应生成。
它还可被用作引发剂,用于通过 o-异氰基二苯基胺的级联自由基加成/环化合成 11-三氟甲基二苯并二氮杂卓。

TBACl 还可被用于与五氧化二磷一起用于更绿色的脱氧氯化反应。

Pr制备卤代杂芳基化合物。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tetrabutylammonium Chloride-Induced Cascade Radical Addition/Cyclization of O-Isocyanodiaryl Amines: A Novel Protocol for the Synthesis of 11-Trifluoromethylated Dibenzodiazepines
Yuan S, et al.
The Journal of Organic Chemistry, 87, 16542-16549 (2022)
Nancy AlHaddad et al.
Organic & biomolecular chemistry, 17(31), 7330-7336 (2019-07-18)
The present study describes the synthesis of the first phenoxycalix[4]pyrrole-epichlorohydrin based polymer. The advantage of the latter resides in its fast-single step synthesis protocol, low cost, water insolubility and its unexpected anion extraction capacity. The study of this polymer by
Efficient and eco-friendly synthesis of 2-amino-4H-chromene derivatives using catalytic amount of tetrabutylammonium chloride (TBAC) in water and solvent-free conditions
Mehrabi H and Kamali N
Journal of the Iranian Chemical Society, 9, 599-605 (2012)
Methyl esterification of carboxylic acids with dimethyl carbonate promoted by K2CO3/tetrabutylammonium chloride
Chau K, et al.
Green Chemistry Letters and Reviews, 6, 89-93 (2013)
I P E Macário et al.
Scientific reports, 9(1), 3932-3932 (2019-03-10)
The tailor-made character of deep eutectic solvents (DES) turns them very attractive to be used in several applications, including in health-related areas such as pharmaceutical, nutraceutical, and cosmetic industries. However, although DES has been touted as "green" solvents, several works

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