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Merck
CN

900148

氧化铁(II,III),纳米颗粒

30 nm avg. part. size (TEM), streptavidin functionalized, 1 mg/mL in H2O

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NACRES:
NA.23
UNSPSC Code:
12352303
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Quality Level

form

dispersion, nanoparticles

packaging

pkg of 1 mL

storage condition

do not freeze

concentration

1 mg/mL in H2O

avg. part. size

30 nm (TEM)

functional group

streptavidin

storage temp.

2-8°C

General description

Recent docking studies highlight the potential interaction of iron oxide (II,III) nanoparticles (IONPs) with the SARS-CoV-2 spike protein receptor binding domain. This may target viral entry in host cells and also render virions inactive.

Application

IONPs may be used in the nanoparticle preparation for evaluation of their antiviral property against H1N1 influenza A virus.
Iron oxide nanoparticles exhibit biocompatibility and non-toxicity and are used as magnetic resonance imaging contrast agents, gene carriers for gene therapy, therapeutic agents for hyperthermia-based cancer treatment, magnetic sensing probes for in vivo diagnostics and for target specific drug delivery.

Legal Information

Product of Ocean Nanotech, LLC.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

法规信息

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商品

Prof. Yadong Yin discusses various synthesis methods of magnetite nanocrystals and their applications in different fields.

Professor Hui Mao explores the use of superparamagnetic iron oxide nanoparticles (INOPs) that offer an alternate contrast-enhancing mechanism.


A Molecular Docking Study Repurposes FDA Approved Iron Oxide Nanoparticles to Treat and Control COVID-19 Infection
Abo-Zeid Y, et al.
European Journal of Pharmaceutical Sciences, 105465-105465 (2020)
Iron oxide nanoparticles based antiviral activity of H1N1 influenza A virus
Kumar R, et al.
Journal of Infection and Chemotherapy, 25(5), 325-329 (2019)
Joan Estelrich et al.
International journal of molecular sciences, 16(4), 8070-8101 (2015-04-14)
In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with



全球贸易项目编号

货号GTIN
900148-1ML04061833219881