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Merck
CN

900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid

≥95%

别名:

Carboxyl sulfonyl fluoride alkyne, Probe building block

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关于此项目

经验公式(希尔记法):
C12H13FO4SSi
化学文摘社编号:
分子量:
300.38
UNSPSC Code:
12352106
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
solid
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assay

≥95%

form

solid

reaction suitability

reagent type: cross-linking reagent

availability

available only in USA

storage temp.

−20°C

SMILES string

O=S(C1=CC(C#C[Si](C)(C)C)=CC(C(O)=O)=C1)(F)=O

InChI key

CNXMDAYMSVWYAS-UHFFFAOYSA-N

Application

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.


象形图

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警示词

Danger

危险代码

Hazard Classifications

Eye Irrit. 2 - Self-react. C - Skin Irrit. 2

存储类别

5.2 - Organic peroxides and self-reacting hazardous materials

怎么回事?

WGK 3

闪点 (F)

Not applicable

闪点 (°C)

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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