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Merck
CN

900607

Sigma-Aldrich

2,5-二溴己二酰胺

≥95%

别名:

2,5-Dibromoadipamide, DBHDA

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About This Item

经验公式(希尔记法):
C6H10Br2N2O2
CAS Number:
分子量:
301.96
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.22

质量水平

方案

≥95%

表单

solid

储存温度

2-8°C

SMILES字符串

BrC(CCC(Br)C(=O)N)C(=O)N

InChI

1S/C6H10Br2N2O2/c7-3(5(9)11)1-2-4(8)6(10)12/h3-4H,1-2H2,(H2,9,11)(H2,10,12)

InChI key

PLSXNAQEJOGNKQ-UHFFFAOYSA-N

应用

This compound has been shown to be a useful reagent for the conversion of cysteine to dehydroalanine (DHA) in peptides or proteins. This enables chemical mutagenesis in which DHA can be efficiently reacted with iodide building blocks to add various natural and unnatural side chains on proteins. It was also shown that other modifications could be added through DHA such as phosphorylation, methylation, and glycosylation. In other research it was shown that DHA can be used to make ubiquitin conjugates that have a bond that mimics the native isopeptide bond.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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