900607
2,5-二溴己二酰胺
≥95%
别名:
2,5-Dibromoadipamide, DBHDA
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关于此项目
经验公式（希尔记法）:
C6H10Br2N2O2
化学文摘社编号:
分子量:
301.96
UNSPSC Code:
12352200
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
solid
Quality Segment
assay
≥95%
form
solid
storage temp.
2-8°C
SMILES string
BrC(CCC(Br)C(=O)N)C(=O)N
InChI
1S/C6H10Br2N2O2/c7-3(5(9)11)1-2-4(8)6(10)12/h3-4H,1-2H2,(H2,9,11)(H2,10,12)
InChI key
PLSXNAQEJOGNKQ-UHFFFAOYSA-N
Application
This compound has been shown to be a useful reagent for the conversion of cysteine to dehydroalanine (DHA) in peptides or proteins. This enables chemical mutagenesis in which DHA can be efficiently reacted with iodide building blocks to add various natural and unnatural side chains on proteins. It was also shown that other modifications could be added through DHA such as phosphorylation, methylation, and glycosylation. In other research it was shown that DHA can be used to make ubiquitin conjugates that have a bond that mimics the native isopeptide bond.
警示词
Warning
危险代码
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable