所有图片(2)
About This Item
经验公式(希尔记法):
C6H10Br2N2O2
CAS Number:
分子量:
301.96
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.22
质量水平
方案
≥95%
表单
solid
储存温度
2-8°C
SMILES字符串
BrC(CCC(Br)C(=O)N)C(=O)N
InChI
1S/C6H10Br2N2O2/c7-3(5(9)11)1-2-4(8)6(10)12/h3-4H,1-2H2,(H2,9,11)(H2,10,12)
InChI key
PLSXNAQEJOGNKQ-UHFFFAOYSA-N
应用
This compound has been shown to be a useful reagent for the conversion of cysteine to dehydroalanine (DHA) in peptides or proteins. This enables chemical mutagenesis in which DHA can be efficiently reacted with iodide building blocks to add various natural and unnatural side chains on proteins. It was also shown that other modifications could be added through DHA such as phosphorylation, methylation, and glycosylation. In other research it was shown that DHA can be used to make ubiquitin conjugates that have a bond that mimics the native isopeptide bond.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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