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Merck
CN

900655

甲氧基聚乙二醇-b-聚(L-丙交酯)

2k-5k

别名:

mPEG-b-PLA, mPEG-PLA, mPEG-PLLA

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关于此项目

线性分子式:
HO[CH(CH3)COO]m[CH2CH2O]nCH3
NACRES:
NA.23
UNSPSC Code:
12162002
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Quality Level

form

powder

storage temp.

2-8°C

Application

由亲水性PEG嵌段和疏水性聚(L-交酯)(PLlA)嵌段组成的生物相容性两亲嵌段共聚物。这些材料已被用于药物封装和递送应用的控释和纳米颗粒制剂中。可通过控制每个聚合物嵌段的相对长度来制备具有各种属性的定义明确材料。羟基封端可实现对这些材料进行进一步的化学修饰。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.


Injectable biodegradable polymeric system for preserving the active form and delayed-release of camptothecin anticancer drugs.
Mert O, et al.
Royal Society of Chemistry Advances, 2(1), 176-185 (2012)
Zhigang Xie et al.
Journal of biomedical materials research. Part A, 88(1), 238-245 (2008-02-21)
Docetaxel (DX) is one of the most effective antineoplastic drugs. Its current clinical administration is limited because of its hydrophobicity and serious side effects. A polymer/DX conjugate is designed and successfully prepared to solve these problems. It is monomethoxy-poly(ethylene glycol)-block-poly(L-lactide)/DX



全球贸易项目编号

货号GTIN
900655-500MG04061833250686