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Merck
CN

900656

甲氧基聚乙二醇-b-聚(L-丙交酯)

5k-10k

别名:

mPEG-b-PLA, mPEG-PLA, mPEG-PLLA

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关于此项目

线性分子式:
HO[CH(CH3)COO]m[CH2CH2O]nCH3
NACRES:
NA.23
UNSPSC Code:
12162002
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Quality Level

form

solid

storage temp.

2-8°C

Application

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(L-lactide) (PLLA) block. These materials have been used in control release and nanoparticle formulation for drug encapsulation and delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

>230.7 °F

flash_point_c

> 110.4 °C

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.


Injectable biodegradable polymeric system for preserving the active form and delayed-release of camptothecin anticancer drugs.
Mert O, et al.
Royal Society of Chemistry Advances, 2(1), 176-185 (2012)
Zhigang Xie et al.
Journal of biomedical materials research. Part A, 88(1), 238-245 (2008-02-21)
Docetaxel (DX) is one of the most effective antineoplastic drugs. Its current clinical administration is limited because of its hydrophobicity and serious side effects. A polymer/DX conjugate is designed and successfully prepared to solve these problems. It is monomethoxy-poly(ethylene glycol)-block-poly(L-lactide)/DX



全球贸易项目编号

货号GTIN
900656-500MG04061833250693