Application
具有生物相容性的两亲嵌段共聚物，由亲水性PEG嵌段和疏水性聚（D,L-丙交酯）（PLA）嵌段组成。这些材料已被用于药物封装和递送应用的控释和纳米颗粒制剂中。可通过控制每个聚合物嵌段的相对长度来制备具有各种属性的定义明确材料。羟基封端可实现对这些材料进行进一步的化学修饰。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.
Zahra Daman et al.
Pharmaceutical research, 32(11), 3756-3767 (2015-08-01)
Resistance to gemcitabine in pancreatic cancer (PC) may account for the failure of conventional treatments. Recently, salinomycin (SAL) has been identified as selective inhibitor of cancer stem cells (CSCs). In our study, we aimed to deliver SAL to gemcitabine-resistant PC
Ho-Chul Shin et al.
Journal of controlled release : official journal of the Controlled Release Society, 140(3), 294-300 (2009-05-05)
Current clinical and preclinical anticancer formulations are limited by their use of toxic excipients and stability issues upon combining different drug formulations. We have found that poly(ethylene glycol)-block-poly(d,l lactic acid) (PEG-b-PLA) micelles can deliver multiple poorly water-soluble drugs at clinically
Yiguang Wang et al.
Pharmaceutical research, 27(9), 1861-1868 (2010-06-19)
To develop an efficient tumor vasculature-targeted polymeric micelle delivery system for combretastatin A4 (CA4), a novel antivascular agent. CA4-loaded micelles were prepared from poly (ethylene glycol)-b-poly (d, l-lactide) copolymers. RGD peptides that target integrins alphavbeta3 and alphavbeta5, markers of angiogenic
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 900658-500MG | 04061833250716 |