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Merck
CN

900672

甲氧基聚乙二醇)-嵌段-聚(ε-己内酯)

5k-10k

别名:

mPEG-b-PCL, mPEG-PCL

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关于此项目

线性分子式:
CH3O(CH2CH2O)n(COCH2CH2CH2CH2CH2O)mH
NACRES:
NA.23
UNSPSC Code:
51171641
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Quality Level

form

powder

transition temp

Tm 61-65 °C

storage temp.

2-8°C

Application

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These materials have been used as a block copolymer surfactant as well as in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.


Xu Wen Ng et al.
Journal of pharmaceutical sciences, 103(11), 3631-3640 (2014-09-17)
Despite the success that drug-eluting stents (DESs) have achieved for minimizing in-stent restenosis (ISR), the antirestenotic agents used in DES have been implicated in delayed endothelial healing and impairment of endothelial functions. Cenderitide (CD-NP) is a novel antiproliferation chimeric peptide
On the mechanism of formation of vesicles from poly(ethylene oxide)-block-poly(caprolactone) copolymers.
Adams DJ, et al.
Soft Matter, 5, 3086-3096 (2009)
Xu Wen Ng et al.
Drug delivery and translational research, 5(5), 469-479 (2015-06-24)
Timolol maleate (TM) has been used for many years for the reduction of intraocular pressure (IOP) in glaucoma patients. However, the topical mode of administration (eyedrops) is far from optimal because of the issues of low bioavailability, high drug wastage



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货号GTIN
900672-500MG04061833250815