4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride

Name: 4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride
Brand: ALDRICH

别名:

Amino sulfonyl fluoride TMS-alkyne, Probe building block

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关于此项目

经验公式（希尔记法）:

C₁₁H₁₄FNO₂SSi

化学文摘社编号:

2088828-95-7

分子量:

271.38

UNSPSC Code:

12352200

NACRES:

NA.22

Form:

liquid

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SMILES string

NC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1

form

liquid

availability

available only in USA

storage temp.

−20°C

Application

Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.