description
2 NHBoc, 1 carboxyl (core)
Quality Segment
form
solid
mol wt
generation 1
no. Surface Groups
2
color
white to off-white
functional group
carboxylic acid (core)
storage temp.
−20°C
General description
- Polymer architecture: Dendron
- End Group Functionality: Boc-protected amine
- Boc : tert-Butyloxycarbonyl
- Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid
Application
Bis-MPA (or 2,2-bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. Both the amine-functionalized dendrimers (after Boc deprotection) and carboxylic acid-functionalized core can be readily used in EDC or DCC coupling reactions with carbonyl or amine-containing compounds, respectively, to yield highly functionalized materials for a variety of biomedical applications.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable