901397
Poly(ethylene glycol) linear dendrimer
NHBoc terminated, PEG Mn 6000, generation 4
别名:
Dendron bifunctionalized PEG, PFD-G4-PEG6k-NHBoc, Polyethylene glycol
产品名称
Poly(ethylene glycol) linear dendrimer, NHBoc terminated, PEG Mn 6000, generation 4
form
solid
mol wt
PEG Mn 6000
color
white to off-white
storage temp.
−20°C
Quality Level
Application
Bis-MPA (or 2,2-bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, making them strong candidates for advanced drug delivery systems or as targeting vessels. Additionally, the terminal amine groups can readily be used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds, to yield highly functionalized materials for a variety of biomedical applications.
General description
- Polymer architecture: Dendron-functionalized PEG
- Generation: 4
- PEG Average Mn: 6,000
- End group functionality: Boc-protected amine
- No. surface groups: 32
- Calculated mol. wt.: 14970.98 g/mol
- Boc: tert-Butyloxycarbonyl
- Bis-MPA: 2,2-bis(hydroxymethyl)propionic acid
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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Yanjun Fu et al.
Bioconjugate chemistry, 17(4), 1043-1056 (2006-07-20)
The purpose of this study was to design, synthesize, and initially characterize a representative set of novel constructs for large-molecular radiographic/computed tomography (CT) contrast agents, intended for a primarily intravascular distribution. A new assembly of well-known and biocompatible components consists
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been
商品
Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).
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