909289
Carboxylic acid-poly(ethylene glycol)-b-poly(D,L lactide)
PEG average Mn 5,000, PDLA average Mn 55,000
别名:
COOH-PEG-PDLA, COOH-PEG-PLA, Carboxylic acid PEG-PDLA, Carboxylic acid-PEG-PLA
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关于此项目
线性分子式:
HO(C3H4O2)m(C2H4O)nC2H3O2
NACRES:
NA.23
UNSPSC Code:
12352106
form
powder or chunks
mol wt
PDLA average Mn 55,000 (by NMR), PEG average Mn 5,000 (by NMR)
color
white to tan
storage temp.
−20°C
Application
Carboxylic acid-poly(ethylene glycol)-b-poly(D,L lactide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable