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Merck
CN

913138

聚(乙二醇)甲醚-嵌段-聚(丙交酯--乙交酯)

PEG average Mn 2,000, PLGA average Mn 10,000, lactide:glycolide 50:50

别名:

mPEG-b-PLGA

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关于此项目

线性分子式:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3
NACRES:
NA.23
UNSPSC Code:
51171641
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Quality Segment

form

powder or solid

feed ratio

lactide:glycolide 50:50

mol wt

PEG average Mn 2,000, PLGA average Mn 10,000 (by NMR)

color

white to beige

storage temp.

−20°C

Application

This polymer is a amphiphilic diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. This biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters.


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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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