915386
Poly(ethylene oxide)-block-poly(butylene oxide)
PEG average Mn 2,000, average Mn 5,000 (PBO)
别名:
PBO-PEO, PEG-PBO, PEO-PBO
产品名称
Poly(ethylene oxide)-block-poly(butylene oxide), PEG average Mn 2,000, average Mn 5,000 (PBO)
form
solid
mol wt
PEG average Mn 2,000 (by NMR)
PEG average Mn 2,000
average Mn 5,000 (PBO(by NMR))
average Mn 5,000 (PBO)
color
white to off-white
PDI
≤1.3 (by GPC)
storage temp.
2-8°C
Quality Level
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Application
Poly(ethylene oxide)-block-poly(butylene oxide) is an amphiphilic block copolymer that shows good biocompatibility. This type of polymers can self-assemble into micelles of various shapes at low concentration. It has been used as nanocarriers to solubilize and delivery hydrophobic drugs.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Guilin Cheng et al.
Colloids and surfaces. B, Biointerfaces, 181, 822-829 (2019-06-28)
Biodegradable polymeric nanoparticles (NPs) have been used frequently as nanocarriers for anticancer drugs. Linoleic acid conjugated SN38 (LA-SN38)-loaded NPs (EBNPs) were developed using biodegradable poly (ethylene oxide)-poly (butylene oxide) (PEO-PBO) diblock copolymer by titration hydration method without using a toxic
Lijiang Wang et al.
Colloids and surfaces. B, Biointerfaces, 161, 464-470 (2017-11-13)
An amphiphilic block copolymer poly(ethylene oxide)-b-poly(butylene oxide) (PEO-PBO) was evaluated as a carrier for therapeutic delivery of paclitaxel (PTX). PEO-PBO and PTX form nanoparticles (NPs) by self-assembly upon hydration. The size of these NPs was about 92.71nm and the zeta
Mahmoud Elsabahy et al.
Biomacromolecules, 8(7), 2250-2257 (2007-06-21)
Poly(ethylene oxide)-block-poly(styrene oxide) (PEO-b-PSO) and PEO-b-poly(butylene oxide) (PEO-b-PBO) of different chain lengths were synthesized and characterized for their self-assembling properties in water by dynamic/static light scattering, spectrofluorimetry, and transmission electron microscopy. The resulting polymeric micelles were evaluated for their ability
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