915599
Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone)
PEG average Mn 2,000, PCL average Mn 5,000
别名:
Carboxylic acid PEG-PCL diblock copolymer, Carboxylic acid-PEG-PCL, PEG-b-PCL, PEG-PCL
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关于此项目
线性分子式:
C3H5O3[C2H4O]n[C6H10O2]mH
UNSPSC Code:
12352106
NACRES:
NA.23
form
powder or chunks
Quality Segment
mol wt
PCL average Mn 5,000 (by NMR), PCL average Mn 5,000, PEG average Mn 2,000 (by NMR), PEG average Mn 2,000
color
white to beige
PDI
≤1.3 (by GPC)
storage temp.
−20°C
SMILES string
[H]OCCCCCC(OCCOCCC(O)=O)=O
InChI
1S/C11H20O6/c12-6-3-1-2-4-11(15)17-9-8-16-7-5-10(13)14/h12H,1-9H2,(H,13,14)
InChI key
RUCUHLNLCAIHAG-UHFFFAOYSA-N
Application
Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable