主要文件

916145

Poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyvalerate-co-(R)-3-hydroxyhexanoate)

Name: Poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyvalerate-co-(R)-3-hydroxyhexanoate)
Brand: ALDRICH

natural origin, PHH content 4.1 %, PHV content 2.3 %

别名:

PHB, PHBH, PHBV, Polyhydroxybutyrate

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关于此项目

线性分子式:

[C₄H₆O₂]_x[C₅H₈O₂]_y[C₆H₁₀O₂]_z

NACRES:

NA.23

UNSPSC Code:

12162002

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属性

form

powder

mol wt

average M_n 1,000,000

composition

3-Hydroxyhexanoic acid content, 4.1% , 3-Hydroxyvaleric acid content, 2.3% , PHH content, 4.1% , PHV content, 2.3%

color

white to off-white

说明

Application

Poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyvalerate-co-(R)-3-hydroxyhexanoate) is a biocompatible and biodegradable polymer produced by fermentation of genetically modified microorganisms. Poly(3-hydroxybutyric acid) (PHB) is a common polyhydroxyalkanoate (PHA), it has been widely used for food packaging, medical implants, biodegradable sutures and drug delivery systems due to its biocompatible and biodegradable properties. PHB has been investigated as drug delivery micro- and nano-carriers.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

MKCN2171

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Advances in the applications of polyhydroxyalkanoate nanoparticles for novel drug delivery system.

Anupama Shrivastav et al.

BioMed research international, 2013, 581684-581684 (2013-08-29)

Drug delivery technology is emerging as an interdisciplinary science aimed at improving human health. The controlled delivery of pharmacologically active agents to the specific site of action at the therapeutically optimal rate and dose regimen has been a major goal

Intracellular delivery of peptide cargos using polyhydroxybutyrate based biodegradable nanoparticles: Studies on antitumor efficacy of BCL-2 converting peptide, NuBCP-9.

Sumeet Kapoor et al.

International journal of pharmaceutics, 511(2), 876-889 (2016-08-06)

Faster biodegradation, immunogenicity and lack of cell penetrative capabilities are hurdles in development of peptidyl drugs for cancer therapy. Polymeric carriers can be used to overcome these problems. The present study is focused on the use of polyhydroxybutyrate as a

Poly(hydroxy acids) in drug delivery.

K Juni et al.

Critical reviews in therapeutic drug carrier systems, 3(3), 209-232 (1987-01-01)

Poly(hydroxy acids) so far have been examined for use in drug delivery in limited number, while the advantageous use of the polymers has been recognized due to their biodegradability and biocompatibility. Homo- and copolymers of lactic acid and glycolic acid

全球贸易项目编号

货号	GTIN
916145-1G	04061842383719