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Merck
CN

922749

Poly(2-methacryloyloxyethyl phosphorylcholine)

Mn 9000

别名:

PMPC

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关于此项目

线性分子式:
(C11H22NO6P)n
UNSPSC Code:
41116105
NACRES:
NA.23
Form:
powder or crystals
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form

powder or crystals

Quality Level

mol wt

Mn 9000

color

white to beige

SMILES string

O=C(OCCOP(OCC[N+](C)(C)C)([O-])=O)C(C)(C)CC

InChI

1S/C13H28NO6P/c1-7-13(2,3)12(15)18-10-11-20-21(16,17)19-9-8-14(4,5)6/h7-11H2,1-6H3

InChI key

SHNPVFQVGKUZPI-UHFFFAOYSA-N

Application

Poly (2-Methacryloyloxyethyl phosphorylcholine) (PMPC) is a methacrylate based polymer with a zwitterionic phosphorylcholine moiety on the side chain. The phosphorylcholine moiety is very similar to the head group of phospholipids in cell membranes. Due to this unique structure, PMPC showed excellent resistance to nonspecific protein adsorption, cell adhesion, and blood coagulation, as well as cell membrane penetration and underwater lubrication. PMPC has been widely exploited in a diverse range of applications, such as antifouling materials for water treatment, bioengineering, and nanomedicine.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Critical update on 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer science
T Goda, et al.
Journal of Applied Polymer Science, 132, 41766-41766 (2015)
Andrew Lewis et al.
Bioconjugate chemistry, 19(11), 2144-2155 (2008-11-01)
The water-soluble, biocompatible polymer poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) was evaluated for protein conjugation. PMPC is a zwitterionic polymer that is able to form a more compact conformation in aqueous solution than poly(ethylene glycol) (PEG). While a terminally functionalized N-hydroxysuccinimide derivative of



全球贸易项目编号

货号GTIN
922749-1G04065266877984