Poly (ethylene glycol)-block-Poly (sulfobetaine methacrylate)

Biocompatible, non-fouling block copolymer composed of a neutral PEG block and a zwitterionic poly(sulfobetaine methacrylate) (PSBMA) block.

Poly(sulfobetaine methacrylate) (PSBMA) is a well-known zwitterionic polymer, it is non-toxic and biocompatible. On each of its repeating unit, it carries both a positive charge and a negative charge, leading to its strong hydration capacity.

Surfaces coated with PSBMA showed super hydrophilic property and strong resistance to protein adsorption/bacterial adhesion, making this polymer a promising material in anti-fouling applications.