929867
Linear polyethylenimine-block-poly(ethylene glycol)
PEG average Mn 2,000, PEI average Mn 30,000
别名:
Nanopatterning, PEG-b-PEI, PEG-PEI, Poly(ethylene glycol)-block-polyethylenimine, block-copolymers
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关于此项目
线性分子式:
CH3(C2H4O)n(C2H5N)mOH
NACRES:
NA.25
UNSPSC Code:
12162002
form
powder or solid
Quality Segment
mol wt
PEG Mn 2000 Da, PEG average Mn 2,000, PEI Mn 30000 Da, PEI average Mn 30,000
color
white to pale yellow
storage temp.
2-8°C
General description
Linear polyethylenimine-block-poly(ethylene glycol) (PEG-b-PEI) is a block copolymer of cationic poly(ethylene imine) (PEI) and hydrophilic poly(ethylene glycol) (PEG). PEI is one of the most commonly used cationic polymers for gene delivery applications and PEG improves nucleic acid delivery by producing a stealth barrier.
Application
Due to their low immunogenicity profiles, polymeric non-viral vectors have shown promise in advancing the treatment of many severe genetic and acquired diseases via gene therapy.
Features and Benefits
Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable