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Merck
CN

933546

NanoFabTx - Natural Folate Lipid Mix

for synthesis of folate functionalized liposomes for targeted delivery

别名:

Cholesterol, EggPC, Folate-PEG-DSPE, PE-PEG

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关于此项目

NACRES:
NA.21
UNSPSC Code:
12352211
Storage temp.:
−20°C
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Quality Segment

storage temp.

−20°C

Application

NanoFabTx Natural Folate Lipid Mix is a ready-to-use nanoformulation lipid mixture for the synthesis of folate-functionalized liposomes. This lipid mix enables users to encapsulate a wide variety of therapeutic drug molecules for targeted drug delivery applications without the need for lengthy trial-and-error optimization.
NanoFabTx Natural Folate Lipid Mix is a lyophilized, curated, lipid mixture containing rationally selected lipids in precise ratios that have been optimized to achieve liposomes of approximately 100nm in diameter. The synthesized folate-functionalized liposomes can be used to selectively target cells which overexpress folate receptors such as HeLa cells and delivery hydrophilic or hydrophobic drugs, including therapeutics that are thermo-sensitive.

Features and Benefits

  • A ready-to-use nanoformulation lipid blend for the synthesis of folate-functionalized liposomes without the need for high temepratures
  • Step-by-step protocols developed and tested by our formulation scientists
  • Flexible synthesis tool to create uniform and reproducible liposomes
  • Optimized to make liposomes around 100 nm with low polydispersity
  • Optimized lipid blend for folate-functionalized liposomes for therapeutic encapsulation
For microfluidic liposome synthesis of azide-functionalized liposomes, the NanoFabTx- Natural Folate Lipid Mix can be used with the the NanoFabTxMicrofluidic - nano device kit (Cat.No. 911593). The NanoFabTxMicrofluidic - nano device kit includes the microfluidics chips, fittings, and tubing required to get started with microfluidics-based synthesis (compatible microfluidics system or syringe pump required).

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC


存储类别

11 - Combustible Solids

wgk

WGK 3



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