934372
MC-Val-Cit-PAB-PNP
≥95%
别名:
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C35H43N7O11
化学文摘社编号:
分子量:
737.76
Beilstein/REAXYS Number:
10322169
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
powder
Quality Segment
assay
≥95%
form
powder
storage temp.
2-8°C
SMILES string
[N+](=O)([O-])c1ccc(cc1)OC(=O)OCc2ccc(cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCCCCN3C(=O)C=CC3=O)C(C)C)CCCNC(=O)N
InChI key
HYSPJPGXSALJRR-DHIFEGFHSA-N
Application
This is a bifunctional cathepsin cleavable linker used in the construction of antibody drug conjugates (ADC).
Features and Benefits
The maleimide functionality can be used for bioconjugation to thiols in monoclonal antibodies while the activated carbonate esters can be used for construction of carbamate linkages with amine containing payloads.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable