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Merck
CN

938858

聚乙烯醇

Polyvinyl alcohol

别名:

Poly(vinyl alcohol), Polyvinyl alcohol

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线性分子式:
[-CH2CHOH-]n
化学文摘社编号:
NACRES:
NA.21
UNSPSC Code:
12352104
MDL number:
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InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

description

80% hydrolyzed

form

crystals

falling ball

2.5-3.5 cP, 4 % in water(20 °C)

application(s)

advanced drug delivery
filtration

Quality Level

Application

NanoFabTx™ Polymers for Microneedles are carefully selected polymers that can be used to formulate microneedle patches. Microneedles are tiny projections of polymeric needles that can vary in length, pitch, and array for topical drug delivery applications. They are typically composed of biodegradable synthetic or natural polymers at a variety of suitable concentrations.
Polyvinyl alcohol (PVA) is a synthetic water-soluble polymer and it widely used in many drug delivery applications. It is a biocompatible polymer which is available in different molecular weights. The formation of the microneedles depends on the molecular weight and concentration of PVA.
The NanoFabTx™ Polymers for Microneedles can be used with the microneedle templates to formulate microneedles that can be used for several applications, such as delivering various therapeutic molecules and vaccine antigens via the skin.
The selected polymer will enable users to:
1) save time in polymer selection by providing a starting point to formulate microneedles and avoiding lengthy trial-and-error optimization.
2)formulate microneedles for various drug delivery applications.

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available

法规信息

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分析证书(COA)

Lot/Batch Number

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Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development
Larra?eta E, et al.
Material Science and Engineering with Advanced Research, 104, 1-32 (2016)
Keegan Braz Gomes et al.
International journal of pharmaceutics, 613, 121393-121393 (2021-12-21)
Effective vaccines delivered via painless methods would revolutionize the way people approach vaccinations. This study focused on the development of fast-dissolving microneedles (MNs) to deliver antigen-loaded sustained release polymeric nanoparticles (NPs), achieving a dual-delivery platform for vaccination through the skin.

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